Can a tracer that hunts unstable iron light up hidden tumors?
NCT ID NCT06942104
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This phase 1 trial is testing whether a new imaging tracer called 18F-TRX can safely and effectively detect solid tumors using PET scans. The tracer targets unstable iron levels, which are often elevated in cancerous tissue. Adults with advanced solid tumors, including certain prostate, kidney, and brain cancers, will receive the tracer and undergo PET/CT imaging. The study aims to see if this approach can clearly visualize tumors and help guide future cancer diagnosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an experimental PET imaging tracer called 18F-TRX (Fluorine F 18 TRX)
- What this could lead to
- If successful, this could provide a new way to detect and visualize a wide range of solid tumors using PET scans, potentially improving cancer diagnosis and monitoring.
- What could go wrong
- This is an early phase 1 trial with a small number of participants, so safety and effectiveness are not yet established. The tracer may not reliably distinguish tumors from healthy tissue.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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