Nerve block may ease radiation pain for anal cancer patients

NCT ID NCT07112690

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a nerve block called ganglion impar neurolysis to see if it can reduce pain caused by radiation therapy for anal cancer. Five adults with localized anal cancer who are getting chemotherapy and radiation will receive the nerve block. Researchers will track pain scores, treatment breaks, and quality of life to see if the procedure helps.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nerve block (ganglion impar neurolysis)

What this could lead to

If it works, this nerve block could help patients complete their cancer treatment with less pain and fewer interruptions.

What could go wrong

This is a very small early study with only 5 participants, so results may not apply to everyone. The procedure carries risks like infection or nerve damage.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anal canal cancer anal canal carcinoma in situ anal carcinoma anal margin carcinoma anus neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University Hospital/Winship Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Grady Health System

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••