Which breathing aid works best for tiny hearts after surgery?

NCT ID NCT05869825

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 200 infants under 1 year old who had heart surgery for congenital heart disease. After their breathing tube is removed, they will get one of two standard breathing supports: High Flow Nasal Cannula or Non-Invasive Positive Pressure Ventilation. The goal is to see which method helps them breathe better and avoids needing the breathing tube again.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

High Flow Nasal Cannula (HFNC) and Non-Invasive Positive Pressure Ventilation (NIPPV)

What this could lead to

If this trial succeeds, it could identify which breathing support method is safer and more effective for infants recovering from heart surgery, potentially reducing the need for re-intubation.

What could go wrong

This is a relatively small, single-center study comparing two standard methods, so results may not apply to all hospitals or infants. The trial is not testing a new drug or cure, so the impact is limited to improving post-surgery care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Arthur M. Blank Hospital | Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30329, United States