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Which breathing aid works best for tiny hearts after surgery?

NCT ID NCT05869825

Recruiting now Disease control Sponsor: Emory University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study looks at 200 infants under 1 year old who had heart surgery for congenital heart disease. After their breathing tube is removed, they will get one of two standard breathing supports: High Flow Nasal Cannula or Non-Invasive Positive Pressure Ventilation. The goal is to see which method helps them breathe better and avoids needing the breathing tube again.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
High Flow Nasal Cannula (HFNC) and Non-Invasive Positive Pressure Ventilation (NIPPV)
What this could lead to
If this trial succeeds, it could identify which breathing support method is safer and more effective for infants recovering from heart surgery, potentially reducing the need for re-intubation.
What could go wrong
This is a relatively small, single-center study comparing two standard methods, so results may not apply to all hospitals or infants. The trial is not testing a new drug or cure, so the impact is limited to improving post-surgery care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

congenital heart disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONGENITAL HEART DISEASE

Contacts and locations

Locations

  • Arthur M. Blank Hospital | Children's Healthcare of Atlanta

    RECRUITING

    Atlanta, Georgia, 30329, United States

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