New hope for hard-to-treat lung cancer: triple-drug attack targets resistant tumors
NCT ID NCT06495125
First seen Apr 07, 2026 · Last updated Jun 05, 2026 · Updated 9 times
Summary
This study tests whether a combination of two targeted drugs (defactinib and avutometinib) plus an immunotherapy drug (nivolumab) can shrink or slow the growth of advanced LKB1-mutant lung cancer that has stopped responding to standard immunotherapy. About 50 adults with this specific type of non-small cell lung cancer will receive the three drugs together. The goal is to see if this approach can control the disease longer than current options.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Emory Saint Joseph's Hospital
RECRUITINGAtlanta, Georgia, 30342, United States
Contact Email: •••••@•••••
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Emory University Hospital Midtown
NOT_YET_RECRUITINGAtlanta, Georgia, 30308, United States
Contact Email: •••••@•••••
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Emory University Hospital/Winship Cancer Institute
RECRUITINGAtlanta, Georgia, 30322, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Conditions
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