ANATOMIC STAGE II BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE II BREAST CANCER AJCC V8 explained in plain language.
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Custom-Made vaccine takes on tough breast cancer
⭐️ VACCINE ⭐️ Recruiting nowThis early-stage trial tests a personalized vaccine made from a patient's own tumor, given alone or with drugs that boost the immune system (pembrolizumab or ipilimumab). The goal is to see if the vaccine is safe and can help the immune system fight triple negative breast cancer …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: ⭐️ VACCINE ⭐️
Last updated May 11, 2026 20:37 UTC
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Could half the treatment be just as good? new trial shortens HER2 therapy for breast cancer
Disease control Recruiting nowThis study is for people with early-stage HER2-positive breast cancer whose tumors completely disappeared after initial chemotherapy and HER2-blocking drugs. It compares 6 months of continued HER2-targeted therapy versus the standard 12 months, to see if the shorter course is jus…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 17, 2026 01:02 UTC
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New drug combo shows promise in shrinking tough breast cancer before surgery
Disease control Recruiting nowThis study tests whether adding the drug darolutamide to standard chemotherapy and immunotherapy before surgery can shrink tumors more effectively in people with early-stage, androgen receptor positive triple-negative breast cancer. About 51 participants will receive either stand…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Vandana Abramson • Aim: Disease control
Last updated May 17, 2026 00:51 UTC
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Could a shorter chemo regimen spare thousands from harsh side effects?
Disease control Recruiting nowThis study compares a shorter chemotherapy-immunotherapy regimen without anthracyclines to the standard longer treatment for people with early-stage triple negative breast cancer. About 2,400 participants will receive either the experimental shorter treatment or the usual care. T…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 15, 2026 12:07 UTC
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Breast cancer survivors: could a common diabetes drug protect your heart and health?
Disease control Recruiting nowThis study looks at whether metformin, a common diabetes medicine, can help prevent or reverse insulin resistance (a step toward diabetes) in women who finished chemotherapy for early-stage breast cancer. About 200 women will either get metformin plus standard diet and exercise a…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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New vaccine combo shows promise in shrinking breast tumors before surgery
Disease control Recruiting nowThis study tests whether adding a cancer vaccine (WOKVAC) to standard chemotherapy and HER2-targeted therapy before surgery can boost the immune system to kill more breast cancer cells. About 25 adults with early-stage HER2-positive breast cancer will receive the vaccine alongsid…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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5-Day breast radiation: a game changer for cancer treatment?
Disease control Recruiting nowThis study tests a new, shorter radiation schedule for women with stage I-III breast cancer. Instead of the usual 3-4 weeks of daily radiation, this approach delivers the entire treatment in just 5 days. The goal is to see if this ultra-fast method is as effective at preventing c…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Immunotherapy boost may stop High-Risk breast cancer return
Disease control Recruiting nowThis large phase III trial tests whether adding the immunotherapy drug durvalumab to standard chemotherapy can prevent breast cancer from coming back in people with a high-risk form of hormone receptor-positive, HER2-negative breast cancer (called MammaPrint High 2 Risk). About 3…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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New study tests cheaper drug for ovarian suppression in breast cancer
Disease control Recruiting nowThis study compares two drugs, leuprolide and goserelin, to see how well they lower estrogen in premenopausal women with breast cancer. Both drugs stop the ovaries from making estrogen, which can fuel cancer growth. The trial will test if leuprolide works as well as goserelin. Ab…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated May 12, 2026 13:42 UTC
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BREAST CANCER BREAKTHROUGH: could less treatment be just as effective?
Disease control Recruiting nowThis study is for people with early-stage triple-negative breast cancer who had a complete response (no cancer left) after chemotherapy plus the immunotherapy drug pembrolizumab. The trial compares receiving more pembrolizumab versus simply being watched (observation) to see if t…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 04, 2026 16:22 UTC
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Laser treatment offers hope for breast cancer survivors suffering from vaginal dryness
Symptom relief Recruiting nowThis study tests a vaginal laser treatment for breast cancer survivors who have vaginal dryness, often caused by cancer treatments like chemotherapy or hormone therapy. About 250 women who finished their main cancer treatment at least a year ago will receive either the laser or a…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated May 17, 2026 00:52 UTC
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Acupuncture may help black women avoid debilitating joint pain during breast cancer treatment
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It focuses on Non-Hispanic Black postmenopausal women with early-stage breast cancer, who are more likely to st…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated May 17, 2026 00:52 UTC
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Shorter radiation before breast surgery may cut side effects
Symptom relief Recruiting nowThis study compares giving a shorter course of radiation (hypofractionated radiotherapy) before versus after breast surgery for people with early-stage breast cancer that hasn't spread. The goal is to see if giving radiation before surgery reduces side effects and treatment time …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 17, 2026 00:50 UTC
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Gentler chemo for seniors: DOROTHY trial aims to cut toxicity without sacrificing results
Symptom relief Recruiting nowThis study is for women aged 65 and older with early-stage HER2-negative breast cancer. It tests whether a lower dose of the chemotherapy drugs docetaxel and cyclophosphamide can still be effective while causing fewer side effects and improving quality of life. About 174 particip…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Stress relief program tested for triple negative breast cancer patients
Symptom relief Recruiting nowThis study tests whether a 10-week stress reduction program is doable and helpful for women with early-stage triple negative breast cancer. The program teaches relaxation, coping skills, and problem-solving, and also connects patients with social services for needs like transport…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Brain food: diet study aims to clear chemobrain in breast cancer patients
Symptom relief Recruiting nowThis study tests whether a 12-week MIND eating plan can ease memory problems, fatigue, and mood issues in 60 women with stage II-III triple-negative breast cancer during chemotherapy. Participants are randomly assigned to the MIND diet or general health coaching, with all session…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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New study aims to help latina breast cancer survivors lose weight and improve health
Symptom relief Recruiting nowThis study tests two remote weight loss programs designed for Latina breast cancer survivors. The goal is to help participants lose weight and improve their health after cancer treatment. Researchers will enroll 640 women who have had breast cancer in the past 5 years and are now…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 11:53 UTC
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Can a hair loss drug help breast cancer patients keep their hair?
Symptom relief Recruiting nowThis study tests whether minoxidil (a hair growth drug) can reduce hair loss caused by hormone therapy in breast cancer patients. About 50 women with stage I-IV breast cancer who are on hormone therapy and have noticed hair thinning will take either a pill or apply a solution to …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Potato power: could a simple starch ease cancer drug side effects?
Symptom relief Recruiting nowThis study tests whether a dietary supplement called resistant potato starch can help prevent joint pain and stiffness caused by aromatase inhibitors, a common breast cancer treatment. About 20 people with early-stage breast cancer or at high risk for it will take the starch whil…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Symptom relief
Last updated May 12, 2026 13:40 UTC
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New study aims to boost Self-Esteem in breast cancer survivors by improving skin health
Symptom relief Recruiting nowThis study looks at whether a skin care program can improve skin quality and self-esteem in breast cancer survivors who are starting a type of hormone therapy called aromatase inhibitors. The study will include 25 women with early-stage breast cancer. Researchers will use special…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 06, 2026 16:02 UTC
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Breast cancer survivors needed for biobank study
Knowledge-focused Recruiting nowThis study collects blood samples and health information from 1,300 women who have had stage I-III breast cancer and finished active treatment. The goal is to create a biorepository for future research into how individual factors affect long-term cancer outcomes. Participants wil…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated May 17, 2026 01:00 UTC
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Gene test could predict breast cancer drug success
Knowledge-focused Recruiting nowThis study looks at whether a specific gene change (HSD3B1) affects how well the drug letrozole works in postmenopausal women with early-stage, hormone-sensitive breast cancer. Researchers will measure changes in tumor markers before and after treatment. The goal is to understand…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE4 • Sponsor: University of Washington • Aim: Knowledge-focused
Last updated May 17, 2026 00:53 UTC
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Can your social life help you beat Cancer's aftermath?
Knowledge-focused Recruiting nowThis study follows 250 young adults (ages 18-39) recently diagnosed with cancer to see how their social relationships and physical activity change over time and affect their quality of life. Researchers will track hospitalizations, treatment details, exercise habits, and well-bei…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated May 17, 2026 00:52 UTC
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New ultrasound marker aims to make breast cancer surgery safer and more precise
Knowledge-focused Recruiting nowThis early-stage study tests a new type of marker that shows up better on ultrasound for people with breast cancer that has spread to lymph nodes. The marker is placed in the affected node to help doctors find and remove it during surgery. The goal is to see if this marker is saf…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC
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New study tracks sleep problems in breast cancer patients
Knowledge-focused Recruiting nowThis study follows 100 women with early-stage, hormone receptor-positive breast cancer to understand how their sleep changes during treatment. Researchers will use sleep watches and questionnaires to measure sleep quality and duration, and explore how stress, social support, and …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:53 UTC
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New tool aims to help women with breast cancer make tough surgery choices
Knowledge-focused Recruiting nowThis study is testing a decision-making tool for women newly diagnosed with early-stage breast cancer. The tool helps them weigh the pros and cons of having a preventive mastectomy on the healthy breast. Researchers want to see if the tool is easy to use, improves knowledge, and …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 08, 2026 12:02 UTC
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Mayo clinic study seeks immune clues in HER2 breast cancer patients
Knowledge-focused Recruiting nowThis study collects blood and tumor tissue from 230 adults with HER2-positive breast cancer (stages I-IV) who are starting anti-HER2 drugs like trastuzumab. Researchers want to learn how the immune system responds to these treatments. The goal is to better understand the connecti…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC
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Gut bacteria linked to chemo side effects?
Knowledge-focused Recruiting nowThis study looks at whether changes in gut bacteria are connected to fatigue and nausea in women receiving chemotherapy for early-stage breast cancer. Researchers will collect stool samples and questionnaires from 70 participants before and after treatment. The goal is to better …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC