New hope for tough breast cancer: drug combo shrinks tumors before surgery

NCT ID NCT07016399

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 20 times

Summary

This study tests whether adding darolutamide, a drug that blocks male hormones, to standard chemotherapy and immunotherapy before surgery can shrink tumors more effectively in people with early-stage androgen receptor positive triple-negative breast cancer. About 51 participants will receive either standard therapy alone or standard therapy plus darolutamide. The goal is to see if the combination reduces tumor size and allows for less extensive surgery.

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Contacts and locations

Locations

  • Vanderbilt University/Ingram Cancer Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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