Can a vaccine train the immune system to hunt down hidden breast cancer cells?
NCT ID NCT07721259
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This phase II trial is testing whether a vaccine called STEMVAC can help prevent triple-negative breast cancer from coming back after surgery. The vaccine targets proteins that cancer cells use to grow and spread, aiming to boost the immune system to destroy any remaining tumor cells. The study enrolls patients who still have moderate or large amounts of cancer left after chemotherapy and surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a multi-antigen DNA vaccine called STEMVAC, given with a GM-CSF immune booster
- What this could lead to
- If it works, this could offer a new way to reduce the risk of breast cancer returning in patients with high-risk triple-negative breast cancer.
- What could go wrong
- This is an early phase II trial with only 60 participants, so results may not apply broadly. The vaccine may cause side effects or fail to improve survival.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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