ANATOMIC STAGE I BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE I BREAST CANCER AJCC V8 explained in plain language.
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Fasting during chemo: a new way to boost treatment?
Disease control Recruiting nowThis trial tests whether time-restricted eating (TRE) — a 16:8 fasting schedule — is feasible for patients with HER2-negative breast cancer undergoing neoadjuvant chemotherapy. Participants will follow TRE for 16 weeks while receiving chemo, and researchers will measure how many …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Thomas Jefferson University • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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Gut bacteria may fortify bones in breast cancer therapy
Disease control Recruiting nowThis phase 2 trial tests whether a probiotic blend called WBF-038 can prevent bone loss in women with early-stage hormone receptor-positive breast cancer who are about to start aromatase inhibitor therapy. Aromatase inhibitors lower estrogen, which can weaken bones. The study wil…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Aug 12, 2026 00:00 UTC
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Could 6 months of therapy be enough for some breast cancer patients?
Disease control Recruiting nowThis phase 3 trial is testing whether 6 months of HER2-targeted therapy (trastuzumab and pertuzumab) works as well as the standard 12 months for people with early-stage HER2+ breast cancer who had a complete response to initial chemotherapy. About 1,500 participants will be rando…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Could breast cancer patients skip extra immunotherapy? major trial aims to find out
Disease control Recruiting nowThis phase 3 trial is for people with early-stage triple-negative breast cancer who had a complete response to chemotherapy plus the immunotherapy drug pembrolizumab before surgery. It compares continuing pembrolizumab for 27 weeks after surgery versus simply watching and waiting…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Aug 07, 2026 00:00 UTC
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Could a common cholesterol drug boost breast cancer treatment?
Disease control Recruiting nowThis trial investigates whether adding simvastatin, a widely used cholesterol medication, to the standard hormone therapy letrozole can better slow the growth of hormone receptor-positive, HER2-negative breast cancer before surgery. About 40 adults with stage I-III breast cancer …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jul 19, 2026 00:00 UTC
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Buttock vs. belly shot: can a simple switch improve breast cancer treatment?
Disease control Recruiting nowThis phase II trial is testing whether giving the hormone therapy drug goserelin (Zoladex) as a shot in the upper buttock works as well as the standard belly injection for suppressing ovarian function in premenopausal women with hormone-positive breast cancer. About 98 patients w…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jul 10, 2026 00:00 UTC
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Could some breast cancer patients skip extra treatment? new trial investigates
Disease control Recruiting nowThis phase II trial is testing whether patients with early HER2-positive or triple-negative breast cancer who had a complete response to pre-surgery treatment and have no cancer DNA in their blood can safely receive less therapy after surgery. The goal is to reduce side effects w…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New study tests cheaper drug to block estrogen in breast cancer
Disease control Recruiting nowThis study compares two drugs, leuprolide and goserelin, to see how well they lower estrogen levels in premenopausal women with breast cancer. Both drugs work by temporarily stopping the ovaries from making estrogen, which can fuel cancer growth. The trial will enroll 75 women an…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New study aims to help latina breast cancer survivors lose weight and improve survival
Disease control Recruiting nowThis study tests two remote weight loss programs designed for Latina breast cancer survivors. Being overweight can worsen breast cancer outcomes, and few programs exist for this group. The study will enroll 640 women who have had breast cancer to see which approach works best for…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Can a common diabetes drug protect breast cancer survivors from insulin resistance?
Disease control Recruiting nowThis phase III trial tests whether metformin, a drug that lowers blood sugar, can prevent or reverse insulin resistance in women with stage I-III breast cancer who have completed chemotherapy. Insulin resistance is a risk factor for diabetes and heart disease, and chemotherapy ma…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Vaccine boosts breast cancer fight before surgery
Disease control Recruiting nowThis study tests whether adding a vaccine called WOKVAC to standard chemotherapy and targeted therapy before surgery can help the immune system better attack HER2+ breast cancer. About 25 adults with early-stage breast cancer will receive the vaccine alongside their regular treat…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Could less chemo be better for older breast cancer patients?
Disease control Recruiting nowThis study looks at whether giving a lower dose of two chemotherapy drugs (docetaxel and cyclophosphamide) can work well and cause fewer side effects in women aged 65 and older with early-stage HER2-negative breast cancer. The goal is to help these women complete their treatment …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Custom-Made vaccine takes on aggressive breast cancer
Disease control Recruiting nowThis early-phase trial is testing a personalized vaccine made from a patient's own tumor, given alone or with immune-boosting drugs (pembrolizumab or ipilimumab), for triple negative breast cancer. The goal is to see if the vaccine is safe and can train the immune system to attac…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 08:15 UTC
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Could radiation before surgery be better for breast cancer?
Disease control Recruiting nowThis phase II trial is testing whether giving a shorter, stronger course of radiation before breast surgery is safer and works better than giving it after surgery for people with non-metastatic breast cancer. The study will enroll 120 participants with different breast cancer typ…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Could a shorter, less toxic treatment be just as effective for early breast cancer?
Disease control Recruiting nowThis study is for people with early-stage triple-negative breast cancer. It compares a shorter chemo-immunotherapy regimen without anthracyclines (a type of strong chemo) to the usual longer treatment. The goal is to see if the shorter approach works just as well while reducing s…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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5-Day radiation for breast cancer: a game changer?
Disease control Recruiting nowThis phase 2 trial is testing a new, ultra-short radiation schedule for women with stage I-III breast cancer who have had a lumpectomy. Instead of the usual 3-4 weeks of daily radiation, this approach delivers the entire course in just 5 days. The goal is to see if this shorter t…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Guiding survivors: navigation program aims to boost access to supportive care
Symptom relief Recruiting nowThis trial tests whether a patient navigation program can help breast cancer survivors schedule and attend appointments for supportive services like counseling, exercise, and nutrition advice. Many survivors have unmet needs for such care, but participation is low, especially amo…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Aug 16, 2026 00:00 UTC
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Digital therapy aims to tame the fear that haunts cancer survivors
Symptom relief Recruiting nowThis trial tests a blended e-health program designed to help women with breast or gynecologic cancer cope with fear of their cancer returning or worsening. The program combines remote group sessions with online modules that teach skills to manage unhelpful thoughts and promote he…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Symptom relief
Last updated Aug 12, 2026 00:00 UTC
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Can a website ease chemo side effects? new study aims to find out
Symptom relief Recruiting nowThis study tests whether an online nutrition education website, Cook for Your Life, can help breast cancer patients manage side effects like diarrhea and constipation during chemotherapy. About 50 adults with stage I-III breast cancer will use the website alongside standard care.…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated Aug 08, 2026 00:03 UTC
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Exercise may sharpen memory in breast cancer survivors
Symptom relief Recruiting nowThis study tests whether a community-based exercise program can improve memory, attention, and brain health in women who have had breast cancer. About 160 survivors, aged 50 and older, will either take part in aerobic exercise or health education sessions. The goal is to see if p…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
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Strawberry compound could help breast cancer survivors walk farther
Symptom relief Recruiting nowThis phase II trial tests whether fisetin, a natural substance found in strawberries, can improve physical function in postmenopausal women who have had chemotherapy for stage I-III breast cancer. Chemotherapy can cause a buildup of aged, non-dividing cells called senescent cells…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jul 19, 2026 00:00 UTC
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Stress-Busting program tested for triple negative breast cancer
Symptom relief Recruiting nowThis study tests whether a 10-week stress reduction program is doable and helpful for people with triple negative breast cancer. The program includes relaxation, coping skills, and social support, and also addresses basic needs like utilities or transportation. Researchers will m…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Virtual workouts may protect heart health in breast cancer patients on chemo
Symptom relief Recruiting nowThis study tests whether a virtual exercise and education program can help breast cancer patients maintain their fitness, heart health, and quality of life while undergoing chemotherapy. About 120 patients with stage I-III breast cancer will be enrolled. Participants will attend …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Laser therapy offers hope for breast cancer survivors suffering from vaginal dryness
Symptom relief Recruiting nowThis study tests a laser treatment for vaginal dryness in breast cancer survivors. Many survivors experience this side effect from cancer treatments like chemotherapy or hormone therapy. The trial will compare the laser to no treatment in 250 women to see if it improves symptoms.
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Potato starch may ease joint pain in breast cancer patients
Symptom relief Recruiting nowThis study tests whether a dietary supplement called resistant potato starch can help prevent joint pain and stiffness caused by aromatase inhibitors, a common breast cancer treatment. About 20 people with stage 0-III breast cancer or at high risk for it will take the supplement …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Michigan Rogel Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Can rogaine help breast cancer patients keep their hair?
Symptom relief Recruiting nowThis early trial tests whether minoxidil (Rogaine) — applied to the scalp or taken as a pill — can help with hair loss caused by hormone therapy in breast cancer patients. About 50 women with stage I-IV breast cancer who report hair thinning since starting endocrine therapy will …
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Acupuncture may help black women avoid debilitating joint pain during breast cancer treatment
Symptom relief Recruiting nowThis study tests whether in-person acupuncture or virtual acupressure can prevent joint pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It focuses on Non-Hispanic Black women with early-stage breast cancer, who are more likely to stop treatment du…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: Emory University • Aim: Symptom relief
Last updated Jun 27, 2026 09:00 UTC
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Nerve grafting may bring back nipple feeling after breast cancer surgery
Symptom relief Recruiting nowThis study looks at whether a nerve graft during nipple-sparing mastectomy can help restore feeling in the nipple. About 20 women with early-stage breast cancer will be randomly assigned to receive the nerve graft or not. The goal is to see if the procedure improves sensation and…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated Jun 27, 2026 08:01 UTC
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Mayo clinic study probes immune secrets of breast cancer drugs
Knowledge-focused Recruiting nowThis study collects blood and tumor samples from 230 adults with HER2-positive breast cancer (stages I-IV) who are starting anti-HER2 drugs like trastuzumab. Researchers want to see how the immune system reacts to these treatments. The goal is to learn more, not to test a new the…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Breast cancer survivors needed for biobank study
Knowledge-focused Recruiting nowThis study collects blood samples and health information from 1,300 women who have had stage I-III breast cancer and finished active treatment. The goal is to create a biorepository that scientists can use in the future to explore links between genes, molecules, and long-term can…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: University of Southern California • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Breast cancer drug's skin side effects under the microscope
Knowledge-focused Recruiting nowThis study looks at how aromatase inhibitor therapy changes skin quality and self-esteem in breast cancer survivors. Researchers will use skin imaging and surveys to track changes in 35 women starting this hormone therapy. The goal is to better understand and manage these side ef…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New tool helps breast cancer patients decide on preventive breast removal
Knowledge-focused Recruiting nowThis study tests a decision-making tool for women newly diagnosed with early-stage breast cancer who are considering removing the healthy breast as a preventive measure. The tool aims to improve knowledge and reduce uncertainty about the choice. Only 15 participants are enrolled,…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Gut bugs linked to chemo side effects? new study investigates
Knowledge-focused Recruiting nowThis pilot study looks at whether changes in gut bacteria are linked to fatigue and nausea in women with early-stage breast cancer undergoing chemotherapy. Researchers will collect stool and blood samples and have participants fill out questionnaires before and after treatment. T…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Breast cancer and sleepless nights: new study investigates the link
Knowledge-focused Recruiting nowThis study looks at how sleep changes in women with early-stage breast cancer during treatment. Researchers will track sleep patterns and check for links to stress, social support, and living environment. About 100 participants will wear a sleep monitor and answer surveys before,…
Matched conditions: ANATOMIC STAGE I BREAST CANCER AJCC V8
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC