Buttock vs. belly shot: can a simple switch improve breast cancer treatment?
NCT ID NCT07460752
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase II trial is testing whether giving the hormone therapy drug goserelin (Zoladex) as a shot in the upper buttock works as well as the standard belly injection for suppressing ovarian function in premenopausal women with hormone-positive breast cancer. About 98 patients who are already on monthly belly injections will switch to buttock injections for 6 months. The main goal is to see if the buttock shot keeps estrogen levels low enough. If it does, it could offer a more comfortable option.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
goserelin acetate (Zoladex)
What this could lead to
If successful, this could offer a more convenient injection site for ovarian suppression, potentially improving comfort and adherence for premenopausal breast cancer patients.
What could go wrong
This is a small, early-phase trial (98 participants) comparing injection sites, not testing a new drug or cure. It may not show a meaningful difference, and results may not apply to all patients.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Phone: •••-•••-••••
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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