Strawberry compound could help breast cancer survivors walk farther

NCT ID NCT05595499

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This phase II trial tests whether fisetin, a natural substance found in strawberries, can improve physical function in postmenopausal women who have had chemotherapy for stage I-III breast cancer. Chemotherapy can cause a buildup of aged, non-dividing cells called senescent cells, which release harmful substances and damage healthy tissue. Fisetin aims to clear these senescent cells, potentially helping survivors walk farther and regain strength.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a naturally occurring substance called fisetin, found in strawberries and other foods
What this could lead to
If it works, this could point toward a way to improve physical function and reduce frailty in breast cancer survivors after chemotherapy.
What could go wrong
This is a small, early-phase trial, so results may not be conclusive. Fisetin may not effectively clear senescent cells or improve physical function in this population.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Comprehensive Cancer Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Health Beverly Hills Primary & Specialty Care

    RECRUITING

    Beverly Hills, California, 90210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Burbank Primary & Specialty Care

    RECRUITING

    Burbank, California, 91505, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Cancer Care in Alhambra

    RECRUITING

    Alhambra, California, 91801, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Primary Care in Marina del Rey

    RECRUITING

    Marina del Rey, California, 90292, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Primary Care in Pasadena

    RECRUITING

    Pasadena, California, 91105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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