Could your gut bacteria predict chemo nausea and fatigue?
NCT ID NCT05417867
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 31 times
Summary
This pilot study at Mayo Clinic is looking at how changes in gut bacteria might be linked to fatigue and nausea in women getting chemotherapy for early-stage breast cancer. Researchers will collect stool and blood samples and have patients fill out questionnaires before and after chemo. The goal is to see if certain gut bacteria patterns are associated with these common side effects, which could help improve future care.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic Health System in Albert Lea
RECRUITINGAlbert Lea, Minnesota, 56007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Mayo Clinic Health System in Mankato
RECRUITINGMankato, Minnesota, 56001, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Mayo Clinic in Arizona
SUSPENDEDScottsdale, Arizona, 85259, United States
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Mayo Clinic in Florida
ACTIVE_NOT_RECRUITINGJacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
SUSPENDEDRochester, Minnesota, 55905, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors understand why some patients get more fatigue and nausea from chemo, possibly leading to better ways to manage these side effects.
What could go wrong
This is a small pilot study (70 people) that only looks for links, not causes. It may not find clear patterns, and results might not apply to all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.