Gut bugs linked to chemo side effects? new study investigates

NCT ID NCT05417867

Recruiting now Knowledge-focused Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study looks at whether changes in gut bacteria are linked to fatigue and nausea in women with early-stage breast cancer undergoing chemotherapy. Researchers will collect stool and blood samples and have participants fill out questionnaires before and after treatment. The goal is to better understand why some patients experience these side effects more than others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could point toward ways to predict or manage fatigue and nausea in breast cancer patients by targeting the gut microbiome.
What could go wrong: This is a small pilot study (70 participants) focused on observation, not treatment. It may not find clear links, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ANATOMIC STAGE I BREAST CANCER AJCC V8 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma chemotherapy-induced toxicity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANATOMIC STAGE I BREAST CANCER AJCC V8 ANATOMIC STAGE II BREAST CANCER AJCC V8 CHEMOTHERAPY-RELATED NAUSEA AND/OR VOMITING EARLY STAGE BREAST CARCINOMA

Contacts and locations

Show contact details

Locations

Mayo Clinic Health System in Albert Lea
RECRUITING

Albert Lea, Minnesota, 56007, United States

Contact Email: •••••@•••••
Mayo Clinic Health System in Mankato
RECRUITING

Mankato, Minnesota, 56001, United States

Contact Email: •••••@•••••
Mayo Clinic in Arizona
SUSPENDED

Scottsdale, Arizona, 85259, United States
Mayo Clinic in Florida
ACTIVE_NOT_RECRUITING

Jacksonville, Florida, 32224-9980, United States
Mayo Clinic in Rochester
SUSPENDED

Rochester, Minnesota, 55905, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.