5-Day radiation for breast cancer: a game changer?
NCT ID NCT06954831
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial is testing a new, ultra-short radiation schedule for women with stage I-III breast cancer who have had a lumpectomy. Instead of the usual 3-4 weeks of daily radiation, this approach delivers the entire course in just 5 days. The goal is to see if this shorter treatment is as good at preventing cancer from coming back while being more convenient and less burdensome for patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy
What this could lead to
If this works, it could offer a much shorter, more convenient radiation schedule for early-stage breast cancer patients after lumpectomy, potentially improving quality of life.
What could go wrong
This is a small, early-phase trial (82 participants) focused on cosmetic outcomes, not survival. The shorter schedule may not be as effective or could have different side effects compared to standard radiation.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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City of Hope Antelope Valley
RECRUITINGLancaster, California, 93534, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope South Pasadena
RECRUITINGSouth Pasadena, California, 91030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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City of Hope Upland
RECRUITINGUpland, California, 91786, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at Arcadia
RECRUITINGArcadia, California, 91007, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at Irvine Lennar
NOT_YET_RECRUITINGIrvine, California, 92618, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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City of Hope at South Bay
RECRUITINGTorrance, California, 90503, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••