Could less chemo be better for older breast cancer patients?

NCT ID NCT06042569

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether giving a lower dose of two chemotherapy drugs (docetaxel and cyclophosphamide) can work well and cause fewer side effects in women aged 65 and older with early-stage HER2-negative breast cancer. The goal is to help these women complete their treatment with less harm to their physical and emotional well-being. About 174 participants will be enrolled to compare the lower dose to the standard dose.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • University of Rochester

    RECRUITING

    Rochester, New York, 14642, United States

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Other studies related to the condition(s) this trial covers.