ANATOMIC STAGE II BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE II BREAST CANCER AJCC V8 explained in plain language.
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Could a vaccine keep triple negative breast cancer from returning?
⭐️ VACCINE ⭐️ OngoingThis phase II trial tests a DNA-based vaccine called STEMVAC in 33 people with early-stage triple negative breast cancer (stages IB-III). The vaccine is designed to train the immune system to recognize and attack cancer cells that express certain proteins. Participants also recei…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:29 UTC
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Could less chemo be enough? new trial for HER2+ breast cancer
Disease control OngoingThis study is for people with HER2-positive stage II to IIIa breast cancer whose tumors completely disappear after initial chemotherapy and targeted therapy before surgery. The goal is to see if using fewer chemotherapy drugs after surgery can still keep the cancer from coming ba…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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New combo aims to stop HER2+ breast cancer relapse
Disease control OngoingThis phase III trial tests whether adding tucatinib to standard T-DM1 therapy works better than T-DM1 alone at preventing breast cancer from coming back. It involves over 1,000 patients with HER2-positive breast cancer who still have cancer cells after initial treatment. The stud…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New targeted therapy combo shows promise for HER2+ breast cancer
Disease control OngoingThis study tests a combination of targeted drugs (ribociclib, tucatinib, trastuzumab, with or without fulvestrant) for HER2-positive breast cancer. In the first part, it looks at safety in patients whose cancer has spread. In the second part, it compares these drugs to standard c…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Can a digital kitchen program help breast cancer survivors eat healthier?
Disease control OngoingThis pilot study tests a remotely-delivered nutrition and cooking program called MIND for stage I-III breast cancer survivors. The program is delivered online through the Cook for Your Life platform and aims to improve diet quality. The study will enroll 49 participants to see if…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Radiation before breast surgery may improve results
Disease control OngoingThis study tests whether giving an extra dose of radiation (a boost) before breast cancer surgery is safe and helpful. About 103 people with early-stage breast cancer that hasn't spread will receive the boost, then standard radiation and surgery. The goal is to see if this approa…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Proton vs X-Ray: which radiation causes fewer side effects in breast cancer?
Disease control OngoingThis study compares two types of radiation therapy—standard x-ray and proton beam—for people with breast cancer who have had surgery. The goal is to see which method causes fewer serious side effects or unplanned surgeries over two years. About 146 adults with stage I to III brea…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Could a common diabetes drug and fasting shrink breast tumors before surgery?
Disease control OngoingThis phase IIb trial is testing whether combining a nightly fast (time-restricted eating) with the diabetes drug metformin can slow the growth of breast cancer cells before surgery. The study includes 120 women with early-stage breast cancer or a precancerous condition called DCI…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Robots take on breast cancer surgery in tiny pilot trial
Disease control OngoingThis pilot study tested whether a robot-assisted surgical technique (using the daVinci system) can safely remove breast tissue while sparing the nipple in people with early-stage breast cancer or those needing preventive mastectomy. Only 4 participants were enrolled, and the stud…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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PET scans may guide breast cancer treatment before surgery
Diagnosis OngoingThis phase 2 trial tests whether a special PET/CT scan using a radioactive tracer (FDG) can predict how well HER2-positive breast cancer responds to standard chemotherapy before surgery. About 235 patients with stage II-III HER2+ breast cancer will get the scan early in treatment…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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New program aims to boost health in older breast cancer survivors
Symptom relief OngoingThis study tests a geriatric care survivorship program for adults aged 65 and older who have finished curative treatment for early-stage breast cancer. The program includes a full health assessment, education, activity tracking, and supportive care. Researchers hope this approach…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:29 UTC
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Texting symptoms may keep young breast cancer patients on treatment
Symptom relief OngoingThis study tests whether regular symptom check-ins via text or email, plus educational materials, can help young women with early-stage breast cancer stay on their hormone therapy. Many women stop treatment early due to side effects. The trial involves 565 women and compares symp…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Picture this: simple photo tool may ease anxiety for breast cancer patients
Symptom relief OngoingThis study tests whether adding a photo guide to standard counseling helps reduce anxiety and depression in women with early-stage breast cancer who are about to start radiation therapy. About 62 participants will either receive standard verbal counseling alone or with a pictoria…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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Walking through chemo: new study tests exercise for older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is practical for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will be asked to walk and do arm exercises several times a week. The goal is to see if exercise can reduce th…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:10 UTC
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New web tool aims to ease symptoms for young breast cancer survivors
Symptom relief OngoingThis study tests a web-based portal called YES (Young, Empowered & Strong) designed to help adolescent and young adult breast cancer survivors monitor and manage their symptoms. Researchers will compare the quality of life of 400 women who use the portal to those receiving standa…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 09:06 UTC
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Writing away the pain: new study tests expressive writing for chinese breast cancer survivors
Symptom relief OngoingThis study looks at whether a culturally tailored writing program can improve the well-being of Chinese immigrant women who had breast cancer (stages 0 to III). About 256 women who finished their main cancer treatment in the last 5 years will write about their experiences. The go…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 08:13 UTC
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Texts and talks: a new way to boost breast cancer Pill-Taking
Symptom relief OngoingThis study tests whether text message reminders and phone counseling help women with early-stage breast cancer take their daily hormone therapy pills as prescribed. About 1,167 women will be split into groups: some get usual care, others get texts and/or motivational interviewing…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated Jun 26, 2026 15:07 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused TerminatedThis study was designed to see if a blood test that looks for tiny pieces of tumor DNA (called ctDNA) could find leftover cancer cells in people with early-stage breast cancer after standard treatment. The goal was to help doctors decide who might need more therapy. However, the …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC
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Can we predict who will get nerve damage from chemo?
Knowledge-focused OngoingThis study aims to find out why some cancer patients develop nerve damage (tingling or numbness in hands and feet) from taxane chemotherapy. Researchers will track over 1,300 people with breast, lung, or ovarian cancer to see how age, gender, and other factors affect their risk. …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Genetic test may predict who gets nerve pain from breast cancer chemo
Knowledge-focused OngoingThis study looks at whether certain genes make African American women with breast cancer more likely to develop nerve damage (pain, numbness, tingling) from common chemotherapy drugs called taxanes. About 249 women with stage I-III breast cancer will receive either docetaxel or w…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:33 UTC
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New study aims to help older breast cancer patients make chemotherapy choices
Knowledge-focused OngoingThis study looks at how women aged 65 and older with early-stage breast cancer decide whether to have chemotherapy before or after surgery. Researchers will use surveys to understand their needs and then create a tool to help patients and doctors make better, shared decisions. Th…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Can ancient ayurveda help cancer survivors? new study tests feasibility
Knowledge-focused OngoingThis study looks at whether two different health programs are practical and acceptable for women who have finished treatment for early-stage breast cancer. One program combines nutrition advice, lifestyle changes, yoga, and therapeutic touch (Ayurveda). The other is a self-guided…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of California, San Francisco • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Study explores fertility hopes after cancer in young women
Knowledge-focused OngoingThis study surveys women aged 18-45 diagnosed with gynecological or breast cancer to understand how they think about having children after treatment. Researchers aim to gather insights that could help future patients and survivors make informed choices about cancer treatment and …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Can smarter radiation save shoulders? new study investigates
Knowledge-focused OngoingThis study follows 61 women with lymph-node positive breast cancer to see how two types of radiation therapy affect shoulder and arm function one year after treatment. Participants receive either intensity-modulated radiation therapy (IMRT) or 3D conformal radiation therapy (3DCR…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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Gene test may guide breast cancer therapy choices
Knowledge-focused OngoingThis study looks at whether a genetic test on tumor samples can predict how well HER2-negative breast cancer will respond to standard treatments like chemotherapy or hormone therapy. About 1,100 people with stage I-III breast cancer are taking part. The goal is to see if this tes…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC