ANATOMIC STAGE II BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE II BREAST CANCER AJCC V8 explained in plain language.
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New vaccine trains immune system to hunt down breast cancer cells
⭐️ VACCINE ⭐️ OngoingThis study tests a DNA-based vaccine called STEMVAC in 33 people with early-stage triple negative breast cancer. The vaccine aims to teach the immune system to recognize and attack proteins found on breast cancer stem cells. The main goal is to see if the vaccine triggers a stron…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated May 17, 2026 02:19 UTC
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Radiation before surgery may improve breast cancer outcomes
Disease control OngoingThis study tests whether giving an extra dose of radiation (a boost) before breast cancer surgery is safe and effective. About 103 people with early-stage, non-metastatic breast cancer will receive the boost, followed by standard radiation and surgery. The goal is to better targe…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Disease control
Last updated May 17, 2026 02:20 UTC
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New drug combo aims to stop aggressive breast cancer in its tracks
Disease control OngoingThis phase 3 study tests whether adding tucatinib to the targeted therapy T-DM1 can better prevent HER2-positive breast cancer from coming back in high-risk patients. About 1,056 participants who still have cancer after initial treatment will receive either T-DM1 alone or T-DM1 p…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 17, 2026 02:05 UTC
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Fasting plus diabetes drug may shrink breast tumors before surgery
Disease control OngoingThis study looks at whether combining a nightly fast (time-restricted eating) with the diabetes drug metformin can reduce breast cancer cell growth in women with early-stage invasive breast cancer or ductal carcinoma in situ (DCIS). About 120 participants will follow the fasting …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Could less chemo be enough for some breast cancer patients?
Disease control OngoingThis study looks at whether women with HER2-positive breast cancer who have no cancer left after initial treatment can safely receive fewer chemotherapy drugs after surgery. About 2,175 participants will get a combination of paclitaxel, trastuzumab, and pertuzumab before surgery,…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Could less be more? new trial reduces breast cancer therapy after full remission
Disease control OngoingThis study looks at whether people with early HER2-positive or triple-negative breast cancer who had a complete response to treatment before surgery can safely receive less therapy after surgery. Participants have no cancer DNA detected in their blood. The goal is to maintain the…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 08, 2026 12:03 UTC
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PET scans may guide breast cancer treatment decisions
Diagnosis OngoingThis study tests whether a special PET/CT scan (FDG-PET/CT) can predict how well HER2-positive breast cancer responds to chemotherapy before surgery. About 235 adults with stage II-III breast cancer will get a scan early in treatment to see if it accurately identifies who will ha…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Diagnosis
Last updated May 11, 2026 20:53 UTC
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Texts and talks: a new way to help breast cancer patients stay on track with meds
Symptom relief OngoingThis study tests whether adding text message reminders and/or telephone counseling helps breast cancer patients take their daily hormone therapy pills more consistently. About 1,167 women with early-stage hormone receptor-positive breast cancer will be followed for up to two year…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Symptom relief
Last updated May 17, 2026 02:06 UTC
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Proton vs X-Ray: which radiation causes fewer side effects for breast cancer patients?
Symptom relief OngoingThis study compares two types of radiation therapy—standard x-ray and proton beam—for women with breast cancer who have had surgery. The goal is to see which method causes fewer serious side effects or unplanned surgeries over two years. About 146 women with stage I to III breast…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Mayo Clinic • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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Mindful eating program aims to boost diet in breast cancer survivors
Symptom relief OngoingThis study tests a remotely-delivered nutrition and mindfulness program for people who had stage I-III breast cancer in the past 5 years. The program uses online cooking lessons and live Q&A sessions to help improve diet quality. Researchers want to see if the program is feasible…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Fred Hutchinson Cancer Center • Aim: Symptom relief
Last updated May 17, 2026 02:05 UTC
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New program aims to boost quality of life for seniors after breast cancer
Symptom relief OngoingThis study looks at whether a special geriatric care program can help older adults (65+) feel better after finishing treatment for early-stage breast cancer. The program includes a full check-up of physical and mental health, plus follow-up visits. Researchers hope this will redu…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 12:07 UTC
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Can a chatbot cure insomnia in breast cancer survivors?
Symptom relief OngoingThis study tests a chatbot called Cecebot that sends personalized text messages to help breast cancer survivors with insomnia. The chatbot combines sleep therapy and physical activity tips to improve sleep and quality of life. About 60 women with stage I-III breast cancer and ong…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Walking through chemo: study tests exercise for older breast cancer patients
Symptom relief OngoingThis study looks at whether a regular exercise program is possible for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants will do walking and arm exercises during their treatment. The goal is to see if exercise can help reduce chemo…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Can yoga and diet help breast cancer survivors? new study aims to find out
Symptom relief OngoingThis study looks at whether two different wellness programs are practical and liked by breast cancer survivors. About 106 people who finished treatment for early-stage breast cancer will be randomly assigned to either an Ayurveda program (with diet, yoga, and touch therapy) or a …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: University of California, San Francisco • Aim: Symptom relief
Last updated May 14, 2026 12:04 UTC
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Can photos ease the fear of breast radiation? new study says yes
Symptom relief OngoingThis study looks at whether adding a simple picture guide to standard counseling can help lower anxiety and depression in women with early-stage breast cancer who are about to start radiation therapy. About 62 women will take part, and their stress levels will be tracked using qu…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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Robots help surgeons perform Nipple-Sparing mastectomy in small pilot study
Symptom relief OngoingThis pilot study tested whether a robot-assisted surgical system (da Vinci) can safely perform nipple-sparing mastectomy in 4 women with early-stage breast cancer or those needing preventive breast removal. The goal was to see if the robot could remove all breast tissue through a…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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New web tool aims to ease life after breast cancer for young women
Symptom relief OngoingThis study tests a web-based portal called YES that helps young breast cancer survivors (ages 15-39) track and manage their symptoms. About 400 women who had early-stage breast cancer within the last 3 years will use the portal or receive standard care. The goal is to see if the …
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 08, 2026 12:02 UTC
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New study aims to keep young breast cancer patients on lifesaving pills
Symptom relief OngoingThis study tests whether regularly checking in on symptoms, along with providing educational materials, helps young women (ages 18-44) with early-stage hormone-positive breast cancer continue taking their hormone therapy as prescribed. Many women stop these pills early due to sid…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: SWOG Cancer Research Network • Aim: Symptom relief
Last updated May 07, 2026 18:39 UTC
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Healing words: writing study aims to ease stress for chinese breast cancer survivors
Symptom relief OngoingThis study looks at whether a culturally tailored expressive writing program can improve quality of life and reduce stress in Chinese immigrant women who had breast cancer (stages 0 to III). About 256 women who finished primary treatment in the last 5 years will write about their…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 05, 2026 11:55 UTC
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Cancer survivors share fertility hopes in new survey
Knowledge-focused OngoingThis study surveys women aged 18-45 who have had gynecological or breast cancer to learn how they think about having a baby after treatment. Researchers will use the results to create better information for patients and survivors about balancing cancer care and family planning. T…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:21 UTC
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New study aims to help older breast cancer patients make chemotherapy choices
Knowledge-focused OngoingThis study looks at how women aged 65 and older with early-stage breast cancer make decisions about chemotherapy. Researchers will interview patients and doctors to understand what information they need. The goal is to create a tool that helps patients and doctors weigh the risks…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:08 UTC
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New study aims to predict who will suffer nerve damage from chemo
Knowledge-focused OngoingThis study follows over 1,300 people with breast, lung, or ovarian cancer who are starting a type of chemotherapy called taxane. The goal is to find out which patients are more likely to develop nerve damage (peripheral neuropathy), which can cause tingling or numbness in the han…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Blood test could spot hidden cancer cells after breast cancer surgery
Knowledge-focused TerminatedThis study looks at whether a blood test that finds tiny bits of tumor DNA can help doctors know if early-stage breast cancer patients still have cancer cells after treatment. About 350 people with stage I-III breast cancer will give blood samples and tumor tissue. The goal is to…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Gene test may guide breast cancer treatment choices
Knowledge-focused OngoingThis study looks at whether testing tumor genes can help predict if HER2-negative breast cancer will respond to chemotherapy or hormone therapy. About 1,100 people with stage I to III breast cancer will have their tumor samples analyzed. The goal is to see if this genetic testing…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated May 17, 2026 02:07 UTC
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Can genes predict chemo nerve damage? new study focuses on african american women
Knowledge-focused OngoingThis study looks at whether certain genes make African American women with breast cancer more likely to develop nerve damage from chemotherapy drugs like docetaxel or paclitaxel. About 249 women with stage I-III breast cancer took part. The goal is to find out if a genetic test c…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 17, 2026 02:03 UTC
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New study tracks shoulder pain after breast cancer radiation
Knowledge-focused OngoingThis study looks at shoulder and arm problems in women with lymph-node positive breast cancer who receive radiation therapy. Researchers want to see how often these problems happen and how severe they are one year after treatment. The goal is to help doctors choose the best radia…
Matched conditions: ANATOMIC STAGE II BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated May 15, 2026 11:53 UTC