CBD oil tested for breast cancer drug side effect

NCT ID NCT06538389

First seen Apr 29, 2026 · Last updated Jun 22, 2026 · Updated 7 times

Summary

This study tests whether a high-CBD plant extract can reduce joint stiffness and pain in women with breast cancer who take aromatase inhibitors. These drugs lower estrogen to prevent cancer return but often cause painful joints, leading some women to stop treatment. The trial will give 36 women either CBD or a placebo to see if CBD helps them stay on their cancer therapy with less discomfort.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

cannabidiol (CBD) plant extract (BRC-001)

What this could lead to

If it works, this could offer a natural way to manage joint pain from breast cancer hormone therapy, helping women stick with their treatment.

What could go wrong

This is a small early-phase trial with only 36 participants, so results may not apply to everyone. CBD can cause side effects like drowsiness or liver issues, and it may not reduce pain better than a placebo.

Conditions

The condition(s) this trial relates to.

breast adenocarcinoma breast cancer breast carcinoma in situ ductal breast carcinoma in situ estrogen-receptor positive breast cancer progesterone-receptor positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.