CBD oil tested for breast cancer drug side effect

NCT ID NCT06538389

First seen Jun 27, 2026 · Last updated Jul 15, 2026 · Updated 2 times

Summary

This study tests whether a high-CBD plant extract can reduce joint stiffness and pain in women with breast cancer who take aromatase inhibitors. These drugs lower estrogen to prevent cancer return but often cause painful joints, leading some women to stop treatment. The trial will give 36 women either CBD or a placebo to see if CBD helps them stay on their cancer therapy with less discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cannabidiol (CBD) plant extract (BRC-001)
What this could lead to
If it works, this could offer a natural way to manage joint pain from breast cancer hormone therapy, helping women stick with their treatment.
What could go wrong
This is a small early-phase trial with only 36 participants, so results may not apply to everyone. CBD can cause side effects like drowsiness or liver issues, and it may not reduce pain better than a placebo.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

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