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Radiation before breast surgery may improve results

NCT ID NCT04871516

Ongoing Disease control Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving an extra dose of radiation (a boost) before breast cancer surgery is safe and helpful. About 103 people with early-stage breast cancer that hasn't spread will receive the boost, then standard radiation and surgery. The goal is to see if this approach reduces side effects and leads to better cosmetic outcomes and tumor control.

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Conditions

The condition(s) this trial relates to.

breast cancer breast carcinoma in situ invasive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANATOMIC STAGE 0 BREAST CANCER AJCC V8 ANATOMIC STAGE I BREAST CANCER AJCC V8 ANATOMIC STAGE IA BREAST CANCER AJCC V8 ANATOMIC STAGE IB BREAST CANCER AJCC V8 ANATOMIC STAGE II BREAST CANCER AJCC V8 ANATOMIC STAGE IIA BREAST CANCER AJCC V8 ANATOMIC STAGE IIB BREAST CANCER AJCC V8 INVASIVE BREAST CARCINOMA NON-METASTATIC BREAST CARCINOMA PROGNOSTIC STAGE 0 BREAST CANCER AJCC V8 PROGNOSTIC STAGE I BREAST CANCER AJCC V8 PROGNOSTIC STAGE IA BREAST CANCER AJCC V8 PROGNOSTIC STAGE IB BREAST CANCER AJCC V8 PROGNOSTIC STAGE II BREAST CANCER AJCC V8 PROGNOSTIC STAGE IIA BREAST CANCER AJCC V8 PROGNOSTIC STAGE IIB BREAST CANCER AJCC V8 PROGNOSTIC STAGE III BREAST CANCER AJCC V8 PROGNOSTIC STAGE IIIA BREAST CANCER AJCC V8 PROGNOSTIC STAGE IIIB BREAST CANCER AJCC V8 PROGNOSTIC STAGE IIIC BREAST CANCER AJCC V8

Contacts and locations

Locations

  • Clara Maass Medical Center

    Belleville, New Jersey, 07109, United States

  • Cooperman Barnabas Medical Center (Saint Barnabas Medical Center)

    Livingston, New Jersey, 07039, United States

  • RWJBarnabas Health - Community Medical Center

    Toms River, New Jersey, 08755, United States

  • RWJBarnabas Health - Monmouth Medical Center Southern Campus

    Lakewood, New Jersey, 08701, United States

  • RWJBarnabas Health - Newark Beth Israel Medical Center

    Newark, New Jersey, 07112, United States

  • RWJBarnabas Health Jersey City Medical Center

    Jersey City, New Jersey, 07302, United States

  • RWJBarnabas Health-Trinitas Hospital and Comprehensive Care

    Elizabeth, New Jersey, 07202, United States

  • Robert Wood Johnson University Hospital Somerset

    Somerville, New Jersey, 08876, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08903, United States

  • Rutgers New Jersey Medical School

    Newark, New Jersey, 07101, United States

  • The Cancer Institute of New Jersey Hamilton

    Hamilton, New Jersey, 08690, United States

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