Strawberry compound and exercise may keep breast cancer survivors from becoming frail

NCT ID NCT06113016

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This phase II trial tests whether a natural supplement called fisetin, found in strawberries, combined with exercise can prevent frailty in postmenopausal women who have had early-stage breast cancer. Fisetin may help clear aging cells that cause inflammation and damage healthy tissue. The study compares fisetin alone, exercise alone, both together, and a placebo to see which approach best maintains physical function.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a natural compound called fisetin, found in strawberries and other foods, given as a nutritional supplement
What this could lead to
If it works, this could point toward a way to prevent frailty in breast cancer survivors, helping them stay active and healthy longer.
What could go wrong
This is an early-phase trial with a moderate number of participants, so results may not be conclusive or apply to all survivors. Fisetin's effects on senescent cells are still being studied.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Health Beverly Hills Primary & Specialty Care

    RECRUITING

    Beverly Hills, California, 90210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Burbank Primary & Specialty Care

    RECRUITING

    Burbank, California, 91505, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Cancer Care in Alhambra

    RECRUITING

    Alhambra, California, 91801, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Primary Care in Marina del Rey

    RECRUITING

    Marina del Rey, California, 90292, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCLA Health Primary Care in Pasadena

    RECRUITING

    Pasadena, California, 91105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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