Can a High-Fiber diet shield the gut during breast cancer therapy?
NCT ID NCT06610097
First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time
Summary
This trial tests whether personalized nutrition counseling to increase fiber intake can help preserve the diversity of gut microbes in people undergoing treatment for early-stage triple-negative breast cancer. Participants are randomly assigned to receive either coaching from a registered dietitian or an educational handout alone. Researchers will analyze stool samples to see how diet, activity, and mood affect the gut microbiome during neoadjuvant therapy, and whether a high-fiber diet offers a protective effect.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- personalized nutritional counseling with a registered dietitian to increase fiber intake
- What this could lead to
- If a high-fiber diet helps preserve gut microbial diversity during treatment, it could point toward a simple, supportive way to improve outcomes and quality of life for breast cancer patients.
- What could go wrong
- This is a small, early-stage trial, so results may not apply broadly. The intervention is supportive and unlikely to replace standard cancer treatment, and its effect on gut health remains uncertain.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Scripps Clinic
La Jolla, California, 92037, United States
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