Could ionized gas help fight breast cancer after surgery?

NCT ID NCT06222788

Recruiting now Disease control Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial tests whether a form of ionized gas, called non-thermal plasma, can be safely applied to the area where a breast tumor was removed during surgery. The goal is to find the highest safe dose and see how well patients tolerate it, while also checking cosmetic effects. Adults with breast cancer scheduled for a lumpectomy may participate, and they will receive a single plasma treatment during their operation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Non-thermal plasma (ionized gas) applied to the tumor bed during surgery
What this could lead to: If safe, this approach could offer a new way to treat the area around a removed breast tumor, potentially reducing the chance of cancer returning.
What could go wrong: This is an early safety trial with only 30 participants, so it may not prove effective. Risks include potential side effects like infection, skin ulcers, or chest wall damage.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER

Contacts and locations

Locations

Centre Hospitalier de l'Université de Montréal - CHUM
RECRUITING

Montreal, Quebec, h2X0A9, Canada

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