RECURRENT BREAST CARCINOMA

This early-stage trial is testing a modified measles virus (MV-s-NAP) that is injected directly into tumors in patients with metastatic breast cancer. The goal is to see if the virus can safely infect and kill cancer cells while also stimulating the patient's immune system to att…

This study is testing whether women whose breast cancer has come back can safely have a second breast-conserving surgery followed by another round of radiation therapy, instead of removing the entire breast. It involves 60 carefully selected patients from two Finnish hospitals wh…

This study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific mutations in genes that help repair DNA damage. It is enrolling 36 adults with various advanced solid tumors (like breast, ovarian, prostate, pancreatic, an…

This early-stage trial is testing a new, personalized vaccine for triple-negative breast cancer (TNBC). The vaccine is custom-made from a piece of a patient's own tumor and is designed to teach their immune system to recognize and attack the cancer. Researchers are studying the v…

This study is testing whether giving a single, precise dose of radiation before a second lumpectomy can help women with recurrent breast cancer. The approach aims to shrink tumors while reducing side effects and preserving breast appearance better than traditional methods. Resear…

This study aims to protect the hearts of people with advanced HER2-positive breast cancer who are receiving a specific treatment (trastuzumab) that can sometimes damage the heart. It is observing nearly 500 patients to see how common heart problems are and testing if a common hea…

This study aims to create a collection of blood and tissue samples from patients whose breast cancer has returned or spread. Researchers will use these samples to learn more about how the cancer changes and responds to treatments over time. The goal is to build a resource that he…