One-Shot radiation before second breast surgery: a new hope for recurrence?
NCT ID NCT06640881
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a single, high dose of radiation given before repeat breast-conserving surgery is safe and effective for women whose breast cancer has returned after previous treatment. The trial will enroll 25 women aged 50 or older with small, low-risk tumors. The goal is to reduce side effects and improve cosmetic results compared to standard post-surgery radiation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
single-dose partial breast irradiation (radiation therapy)
What this could lead to
If successful, this approach could offer a less toxic, more cosmetic-friendly option for women with recurrent breast cancer, potentially reducing the need for mastectomy.
What could go wrong
This is a small, early-phase trial with only 25 participants, so results may not apply to all patients. The main risk is radiation-related side effects, and it is not yet known if this approach controls cancer as well as standard treatments.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Amsterdam UMC / VU Medical Centre
RECRUITINGAmsterdam, Netherlands
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••