Genetic clues in blood and tumors could personalize breast cancer care
NCT ID NCT03281902
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at genetic changes in blood and tumor samples from women with advanced hormone receptor-positive, HER2-negative breast cancer who are being treated with palbociclib and endocrine therapy. By comparing genetic material from the cancer tissue with that found in the blood, researchers hope to identify markers that predict how well the treatment works. The goal is to pave the way for more customized treatment approaches for this type of breast cancer.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors develop more personalized treatment plans for advanced breast cancer by identifying genetic markers linked to treatment response.
- What could go wrong
- This is an observational study focused on genetic analysis, not a treatment trial. It may not directly lead to new therapies, and results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Mayo Clinic in Arizona
Scottsdale, Arizona, 85259, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224-9980, United States
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
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