Gene test could guide breast cancer treatment to boost survival
NCT ID NCT02276443
First seen Jul 15, 2026 · Last updated Jul 16, 2026 · Updated 1 time
Summary
This study tests whether analyzing the genetic makeup of a patient's triple-negative breast cancer tumor can help doctors choose the most effective treatment. Patients with newly diagnosed, early-stage triple-negative breast cancer receive either standard chemotherapy or a personalized treatment plan based on their tumor's genetic signature. The goal is to see if this tailored approach leads to better tumor shrinkage and survival compared to standard care alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- standard chemotherapy or immunotherapy, assigned based on tumor genomic testing
- What this could lead to
- If successful, this approach could lead to more effective, personalized treatment plans for triple-negative breast cancer, potentially improving survival rates.
- What could go wrong
- This is an early-stage framework study, not a direct test of a new drug. The personalized approach may not improve outcomes over standard care, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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M D Anderson Cancer Center
Houston, Texas, 77030, United States
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MD Anderson League City
League City, Texas, 77573, United States
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MD Anderson West Houston
Houston, Texas, 77079, United States
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MD Anderson in Sugar Land
Sugar Land, Texas, 77478, United States
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MD Anderson in The Woodlands
Conroe, Texas, 77384, United States
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