Can freezing breast tumors replace the scalpel?
NCT ID NCT07775014
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This trial is investigating whether cryoablation, a technique that freezes and destroys breast tumors with extreme cold, can be an effective alternative to surgery for certain patients. The study will include adults with localized breast cancer who cannot or choose not to have surgery, as well as some postmenopausal women with small, low-risk tumors. Participants will receive ultrasound-guided cryoablation and then be monitored with imaging to see if the tumor is completely destroyed and if the procedure is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Percutaneous cryoablation, a procedure that uses extreme cold to freeze and destroy breast tumors through thin needles guided by ultrasound.
- What this could lead to
- If successful, this could offer a non-surgical treatment option for certain breast cancer patients, potentially reducing the need for surgery and its associated recovery.
- What could go wrong
- This is a small, early-stage study, so results may not apply to all patients. There is a risk the tumor may not be completely destroyed, and follow-up imaging may not reliably detect residual disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ospedale Cottolengo
Torino, TO, 10152, Italy
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