Can a new infusion drug shrink Hard-to-Treat breast tumors?
NCT ID NCT07774624
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This trial is testing an investigational drug called SKB103 in people with advanced HER2-negative breast cancer that has not responded to standard treatments. The study has two parts: first, to find a safe dose, and second, to see how well that dose shrinks tumors. Participants receive SKB103 by intravenous infusion every three weeks. The goal is to determine if this drug can control the disease and improve outcomes for this patient group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SKB103, an investigational drug given by intravenous infusion every three weeks
- What this could lead to
- If successful, SKB103 could offer a new treatment option for people with advanced HER2-negative breast cancer who have run out of standard therapies.
- What could go wrong
- This is an early-phase trial, so the drug may not work as hoped or may cause side effects. Success in this trial does not guarantee approval or benefit for all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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