Can a new PET tracer spot breast cancer spread better than standard scans?
NCT ID NCT05889728
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This trial is testing whether a new PET imaging agent called NeoB can more accurately detect the spread of a certain type of breast cancer (ER/PR positive, HER2 negative) compared to conventional scans like CT, bone scans, and FDG PET/CT. The study will enroll 20 women with metastatic breast cancer who need imaging to stage or restage their disease. Each participant will receive an injection of the NeoB tracer followed by a PET/CT scan, and the results will be compared to standard imaging and biopsy findings to assess diagnostic accuracy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A radioactive imaging agent called [68Ga]Ga-NeoB, given as an injection for PET/CT scans to detect breast cancer spread.
- What this could lead to
- If successful, this imaging method could improve the accuracy of staging metastatic breast cancer and help select patients for targeted radiation therapy.
- What could go wrong
- This is a small early-phase pilot study with only 20 participants, so results may not apply broadly. The imaging agent's accuracy and safety are still being evaluated.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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St Vincent's Hospital
Sydney, New South Wales, 2010, Australia
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