ADVANCED BREAST CARCINOMA

This early-stage trial is testing the safety of combining a wearable device that uses electric fields to disrupt cancer cells with different drug combinations. It is for adults with advanced cancers in the abdomen or chest that have spread and who have run out of standard treatme…

This study is testing two new drug combinations for people with advanced, BRCA-positive breast cancer that has spread and has stopped responding to a standard type of targeted therapy (PARP inhibitors). The trial will see if adding a second drug to the standard one can shrink tum…

This study is testing whether giving standard cancer treatments at home is as safe and effective as giving them in a clinic. It aims to see if receiving care at home reduces stress, improves quality of life, and is preferred by patients with advanced cancers. About 220 participan…

This early-stage study is testing the safety and best dose of a new two-drug combination for people with advanced solid tumors that have a specific marker called HER2. The treatment pairs an existing targeted cancer drug with a new pill that aims to block cancer cells' ability to…

This study is for people with a specific, harder-to-treat type of advanced breast cancer that is hormone-sensitive but has a non-luminal genetic pattern. It will compare a newer drug called trastuzumab deruxtecan against the current standard treatment (a CDK4/6 inhibitor plus hor…

This study aims to learn from people living with advanced breast cancer and their caregivers about their experiences with care and support. Researchers will survey and interview 50 participants across four groups to understand what has been helpful, what has been difficult, and w…