Electric field device combined with drugs tested for advanced cancers
NCT ID NCT05092373
First seen Jun 26, 2026 · Last updated Jul 17, 2026 · Updated 3 times
Summary
This early-phase trial tests a wearable device that creates electric fields (tumor treating fields) combined with either cabozantinib or nab-paclitaxel and atezolizumab in 43 people with advanced solid tumors in the abdomen or chest. The goal is to find the safest dose and see if the combination helps control tumor growth. Participants must have tried standard treatments without success.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tumor Treating Fields (electrical fields from a wearable device) plus either cabozantinib or nab-paclitaxel and atezolizumab
- What this could lead to
- If successful, this could point toward a new combination treatment that helps control advanced solid tumors in the abdomen or chest.
- What could go wrong
- This is a very early phase 1 trial with only 43 participants, so safety and dosing are still being figured out. The approach may not work or could cause side effects.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
M D Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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