STAGE IV OVARIAN CANCER AJCC V8
Clinical trials for STAGE IV OVARIAN CANCER AJCC V8 explained in plain language.
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New hope for Hard-to-Treat ovarian cancer: PLX038 trial launches
Disease control Recruiting nowThis study tests a drug called PLX038 in people with ovarian, fallopian tube, or peritoneal cancer that has spread and no longer responds to platinum chemotherapy. The goal is to see if PLX038 can shrink tumors. About 43 adults with advanced cancer will receive the drug, and rese…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 16, 2026 22:57 UTC
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New drug combo aims to shrink returning gynecologic tumors
Disease control Recruiting nowThis early-stage study tests a drug called talazoparib together with radiation therapy for people whose gynecologic cancer (like ovarian, endometrial, or cervical) has returned after previous treatment. The main goal is to find the safest dose and see how well the combination wor…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 16, 2026 22:48 UTC
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Could a less invasive surgery help ovarian cancer patients live longer and better?
Disease control Recruiting nowThis study tests if a less invasive surgery (laparoscopy) works as well as or better than standard open surgery for people with advanced ovarian, fallopian tube, or peritoneal cancer who have already had chemotherapy. About 580 participants will be randomly assigned to one of the…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE3 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 16, 2026 22:44 UTC
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Heated chemotherapy during surgery: a new hope for ovarian cancer?
Disease control Recruiting nowThis study tests the safety of giving heated chemotherapy directly into the abdomen during surgery for advanced ovarian, fallopian tube, or peritoneal cancer. About 45 people will receive either the heated treatment after surgery or standard chemotherapy before surgery. The goal …
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New drug combo trial hopes to tame tough cancers
Disease control Recruiting nowThis early-phase study tests a new drug called IACS-6274, given alone or with other medicines, in people with advanced solid tumors (like certain melanomas, ovarian, and uterine cancers). The main goal is to find the safest dose and understand side effects. About 54 adults will t…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New hope for advanced cancers with DNA repair flaws: PARP inhibitor trial opens
Disease control Recruiting nowThis study tests the drug talazoparib in adults with advanced solid tumors (like breast, prostate, ovarian, pancreatic, or stomach cancer) that have certain gene changes affecting DNA repair. The drug blocks a protein called PARP, which cancer cells need to fix their DNA, potenti…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Electric field device shows promise in taming advanced cancers
Disease control Recruiting nowThis early-phase study tests a wearable device that creates low-intensity electric fields (tumor treating fields) combined with either cabozantinib or a chemo-immunotherapy pair (nab-paclitaxel and atezolizumab) in people with advanced solid tumors in the abdomen or chest. The go…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:46 UTC
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Probiotics may boost gut health in ovarian cancer chemo
Disease control Recruiting nowThis study tests whether taking probiotics (friendly bacteria) can improve gut and vaginal health in 161 women with advanced or recurrent ovarian cancer who are receiving platinum chemotherapy. Researchers will check changes in the microbiome, quality of life, and symptoms. The g…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated May 11, 2026 20:41 UTC
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Chemo mist shows promise for abdominal cancers in early trial
Disease control Recruiting nowThis early-stage study is testing a new method called PIPAC, which turns chemotherapy into a fine mist and sprays it directly into the abdomen during a keyhole surgery. The goal is to see if this approach is safe and can reduce side effects compared to standard chemotherapy. Abou…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 11, 2026 20:39 UTC
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Could a simple wash detect ovarian cancer before it spreads?
Diagnosis Recruiting nowThis study aims to develop a test that finds ovarian cancer earlier by looking at DNA from a uterine wash and proteins in the blood. Researchers will collect samples from 250 women before surgery for a suspected ovarian mass or as a preventive measure. The goal is to see if these…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Sponsor: Massachusetts General Hospital • Aim: Diagnosis
Last updated May 16, 2026 22:44 UTC
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Smartwatch study aims to boost exercise and quality of life in ovarian and endometrial cancer patients
Symptom relief Recruiting nowThis study tests whether a personalized activity program using a Fitbit can help people with ovarian or endometrial cancer exercise more and improve their quality of life. About 120 participants will either get the program or standard advice. The goal is to see if the program hel…
Matched conditions: STAGE IV OVARIAN CANCER AJCC V8
Phase: NA • Sponsor: Roswell Park Cancer Institute • Aim: Symptom relief
Last updated May 16, 2026 22:44 UTC