Heated chemo during surgery: a new hope for ovarian cancer?

NCT ID NCT05415709

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial is testing whether giving heated chemotherapy directly into the abdomen during surgery is safe for people with advanced ovarian, fallopian tube, or peritoneal cancer. Participants will receive standard chemotherapy before surgery, and then either heated chemo during surgery or extra chemo the day before. The study aims to see which approach has fewer side effects and is more practical.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cisplatin (heated chemotherapy given into the abdomen during surgery)

What this could lead to

If this approach is safe and feasible, it could lead to a larger trial testing whether heated chemotherapy during surgery helps people with advanced ovarian cancer live longer.

What could go wrong

This is a very early (Phase 1) trial with only 45 people. It is designed to check safety, not effectiveness. Heated chemotherapy can cause serious side effects like infection, organ damage, or blood clots.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

fallopian tube cancer fallopian tube endometrioid adenocarcinoma fallopian tube mucinous adenocarcinoma fallopian tube neoplasm fallopian tube serous adenocarcinoma ovarian cancer ovarian carcinoma ovarian endometrioid adenocarcinoma ovarian mucinous adenocarcinoma ovarian serous adenocarcinoma primary peritoneal carcinoma primary peritoneal serous adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-••••

    Contact