Could a simple wash catch ovarian cancer before it spreads?

NCT ID NCT04794322

Recruiting now Diagnosis Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study is testing a new way to detect ovarian cancer early. Researchers will take a sample of fluid from the womb (uterine lavage) and a blood sample from 250 women before they have surgery for a suspected ovarian growth. After surgery, they will check whether the woman had cancer or a benign condition. The goal is to see if DNA from the wash and proteins in the blood can accurately tell the difference. If the test works, it might one day help catch ovarian cancer earlier and save lives.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple test that catches ovarian cancer earlier, potentially reducing deaths from the disease.
What could go wrong: This is an early-phase biomarker study, not a treatment trial. The test may not work as well in women without symptoms, and further studies are needed to confirm its accuracy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for FALLOPIAN TUBE CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Carcinoma, Ovarian Epithelial fallopian tube cancer fallopian tube neoplasm neoplasm ovarian cancer ovarian carcinoma ovarian disorder ovarian epithelial tumor ovarian neoplasm ovarian serous adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FALLOPIAN TUBE NEOPLASMS HIGH GRADE OVARIAN SEROUS ADENOCARCINOMA OVARIAN EPITHELIAL CARCINOMA OVARIAN NEOPLASMS STAGE I OVARIAN CANCER STAGE II OVARIAN CANCER STAGE III OVARIAN CANCER AJCC V8 STAGE IIIA OVARIAN CANCER AJCC V8 STAGE IIIA1 OVARIAN CANCER AJCC V8 STAGE IIIA2 OVARIAN CANCER AJCC V8 STAGE IIIB OVARIAN CANCER AJCC V8 STAGE IIIC OVARIAN CANCER AJCC V8 STAGE IV OVARIAN CANCER AJCC V8 STAGE IVA OVARIAN CANCER AJCC V8 STAGE IVB OVARIAN CANCER AJCC V8

Contacts and locations

Locations

Anne Arundel Health System
RECRUITING

Annapolis, Maryland, 21401, United States
Johns Hopkins University School of Medicine
RECRUITING

Baltimore, Maryland, 21218, United States
Kaiser Permanente - San Francisco
ACTIVE_NOT_RECRUITING

San Francisco, California, 94115, United States
Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114, United States
The Swedish Hospital
RECRUITING

Seattle, Washington, 98122, United States
University of Arkansas for Medical Sciences
RECRUITING

Little Rock, Arkansas, 72205, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.