Can heated chemo during surgery help older women with ovarian cancer?
NCT ID NCT07733505
First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time
Summary
This study tests whether giving heated chemotherapy directly into the abdomen during surgery is safe for women aged 70 and older with advanced ovarian cancer. The treatment, called NIPEC with carboplatin, is delivered at normal body temperature for 90 minutes right after the surgeon removes visible tumors. Researchers will closely monitor complications, recovery, and quality of life to see if this approach allows frail patients to complete standard chemotherapy afterward.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Normothermic intraperitoneal chemotherapy with carboplatin
- What this could lead to
- If safe and feasible, this approach could offer a treatment option for elderly or frail ovarian cancer patients who may not tolerate standard therapy.
- What could go wrong
- This is a very small early-phase study with only 10 participants, so results may not apply broadly. The chemotherapy is given directly into the abdomen, which carries risks of infection, organ damage, and side effects from carboplatin.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Odense University Hospital
RECRUITINGOdense, 5000, Denmark
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