Odense University Hospital

This study tests whether a weekly dose of everolimus (a drug similar to rapamycin), resistance training three times a week, or both together can improve bone formation in women aged 60-75 with low bone mass. Researchers will measure bone markers, density, and muscle function over…

This study tests whether removing a larger portion of the mesentery (the tissue that connects the intestine to the abdominal wall) during surgery for Crohn's disease can reduce the chance of the disease coming back. 204 adults with Crohn's disease limited to the ileocecal area wi…

This study tests whether fecal microbiota transplants (FMT) given as capsules can safely improve symptoms in people newly diagnosed with rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, Crohn's disease, or ulcerative colitis. Two hundred participants will receiv…

This study tests whether removing cow's milk protein from the diet (via mother's diet or special formula) works better than the drug omeprazole for treating gastroesophageal reflux disease (GERD) in infants under 1 year old. About 96 babies with GERD will be randomly assigned to …

This study compares two ways to take tissue samples from small lung spots found during screening. One method uses standard forceps, the other uses a freezing probe (cryo biopsy) to get larger samples. The goal is to see if cryo biopsies give a clearer diagnosis with fewer complic…

This study is testing whether a camera capsule that you swallow can be used as a first step to check for colorectal cancer, instead of going straight to a colonoscopy. The capsule takes pictures as it travels through your gut, and if it finds something suspicious, you would still…

This study tests whether adding a short interpretive comment to blood test results for high cholesterol can encourage doctors to refer more patients to specialized lipid clinics. The goal is to increase detection of familial hypercholesterolemia, a common inherited condition that…

This study is testing whether a tiny camera in a pill (colon capsule endoscopy) can find colorectal cancer or precancerous growths in people who have had a bloodstream infection with certain gut bacteria. About 100 adults will swallow the camera 4-8 weeks after leaving the hospit…

This study tests whether drinking carrot juice rich in natural compounds called polyacetylenes can stop new polyps from growing in people who have already had large or high-risk polyps removed. Four hundred participants will drink either special carrot juice or a placebo juice da…

This study tests whether washing the bladder with a harmless strain of E. coli can prevent recurrent urinary tract infections (UTIs) in people who have failed other treatments. Researchers will compare the harmless bacteria wash to a saltwater wash in 80 participants, tracking ho…

This study tests whether methylphenidate, a drug used for ADHD, can reduce severe fatigue in people who had a brain tumor as a child or teen. Fifty survivors aged 6 and older will receive either the drug or a placebo in a crossover design. The goal is to see if it improves energy…

This study tests whether a 24-week Frame Running training program can improve physical function, daily activity, and quality of life in children aged 8-18 with cerebral palsy or similar physical disabilities. Participants start with a low-intensity 12-week period, then move to a …

This study looks at whether a less restrictive ankle stirrup works as well as a standard walker boot for pain and daily function after an ankle fracture. About 1400 adults who had surgical or non-surgical treatment will be randomly assigned to one brace type. The goal is to see i…

This study looks at whether placing infants with breathing problems from infections like RSV on their stomach (prone) helps them breathe better than lying on their back (supine). Forty babies under 1 year old on breathing support will be placed in each position for one hour. Rese…

This study tests a group-based psychological program called ACTnow for emerging adults (ages 18-35) with type 1 diabetes who feel overwhelmed by their condition. The program includes six bi-weekly sessions led by a psychologist and nurse, focusing on mindfulness and acceptance st…

This study compares robot-assisted training to standard physical therapy for people who have had a stroke and still have moderate-to-severe movement problems. Forty participants who are 6-24 months post-stroke will be randomly assigned to one of two training programs. The goal is…

This study tests a 12-week prehabilitation program for 20 prostate cancer patients about to start hormone and radiation therapy. The program includes physical exercise and a 4-day residential session with education and activities. Researchers want to see if patients and their fam…

This study looks at whether people aged 70 and older experience changes in thinking skills, like attention and processing speed, after same-day hip or knee replacement surgery. About 48 participants will take a short cognitive test before surgery and again on the first and sevent…

This study looks at a rare but serious condition called calciphylaxis, where small blood vessels in the skin harden, often leading to death. Researchers will compare 860 adults with chronic kidney disease—some who have calciphylaxis and some who don't—to find clues about what cau…

This study compares two types of scans—FDG-PET/CT and standard CT—to see which one better tracks breast cancer that has spread. Researchers want to know if the newer scan can find cancer growth earlier, helping doctors start new treatments sooner and potentially extend patients' …

This study looks at different ways to surgically fix a broken hip in adults under 65. The main goal is to see if a new implant keeps the bone more stable during healing compared to standard screws. Researchers will use a special X-ray method to measure any movement in the fractur…

This study aims to understand why the Achilles tendon becomes painful and swollen in people with psoriatic arthritis. Researchers will take small tissue samples from the tendon and look for immune cells and inflammatory markers. The goal is to learn more about the disease, not to…

This study follows up on mothers and their 14-year-old children from a previous trial where pregnant women with obesity were given diet and exercise advice. Researchers want to see if those lifestyle changes during pregnancy affected the children's body fat and health as teenager…

This study looks at how cancer affects not just patients, but their entire family. Researchers will survey 240 Danish patients with breast, prostate, colorectal cancer, or lymphoma, along with their caregivers. They will measure family health, stress, depression, and quality of l…