Friendly bacteria bladder wash aims to stop UTIs without antibiotics

NCT ID NCT04846803

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether washing the bladder with a harmless strain of E. coli can prevent recurrent urinary tract infections (UTIs) in people who have failed other treatments. Researchers will compare the harmless bacteria wash to a saltwater wash in 80 participants, tracking how many UTIs occur over time. If successful, this could offer an antibiotic-free prevention option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-pathogenic E. coli bacteria (ABU strain) for bladder lavage

What this could lead to

If it works, this could offer a new way to prevent recurrent UTIs without antibiotics, reducing the need for frequent medication.

What could go wrong

This is a small, early-stage trial (80 people) testing a novel approach. The bacteria may not outcompete harmful strains in all patients, and long-term effectiveness is unknown.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

escherichia coli infection urinary tract infection urinary tract infections, recurrent, susceptibility to

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Aarhus University Hospital

    RECRUITING

    Aarhus N, 8200, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Odense University Hospital

    RECRUITING

    Odense C, 5000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••