Should you remove kidney stones to stop UTIs? study seeks answers

NCT ID NCT04495699

Completed Knowledge-focused Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study followed 94 adults who have both recurrent urinary tract infections and kidney stones that are not blocking the kidney. Researchers wanted to see if surgically removing these stones reduces the number of future UTIs compared to just monitoring them. Patients chose with their doctor whether to have stone removal or not, and the team tracked infections for a year. The goal is to provide better guidance for treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors decide whether to remove silent kidney stones to prevent repeat UTIs.
What could go wrong: This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis urinary tract infection urinary tract infections, recurrent, susceptibility to urolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

KIDNEY STONE URINARY TRACT INFECTIONS

Contacts and locations

Locations

Columbia University

New York, New York, 10027, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Mayo Clinic Arizona

Phoenix, Arizona, 85054, United States
University of California San Diego

San Diego, California, 92093, United States
Vancouver General Hospital/University of British Columbia

Vancouver, British Columbia, V6T1Z4, Canada
Vanderbilt University Medical Center

Nashville, Tennessee, 37232, United States

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