URINARY TRACT INFECTIONS

This study tests a new vaccine designed to prevent urinary tract infections (UTIs) caused by E. coli bacteria. It involves 448 adults aged 18-64, with a focus on safety and immune response in all participants, and early effectiveness in women. The vaccine is given as a shot and c…

This study tests two approaches to prevent repeat urinary tract infections (UTIs) in 100 women aged 40 and older who have gone through menopause. One group takes a nightly antibiotic pill for 6 months, while the other uses a vaginal tablet containing healthy bacteria and a low do…

This study tests a new treatment called LBP-EC01, which uses special viruses (bacteriophages) to attack drug-resistant E. coli bacteria that cause urinary tract infections (UTIs). About 318 adults with a history of UTIs and a current infection will receive either LBP-EC01 plus an…

This study looks at whether giving antibiotics by mouth (orally) works as well as giving them through a vein (IV) for people who come to the emergency room with common infections like pneumonia, urinary tract infections, or skin infections. About 4,000 adults will take part, and …

This study tests a new DNA-based method (Next Generation Sequencing) to detect bacteria in urine from women with UTI symptoms whose standard urine culture shows very few bacteria. The goal is to see if this advanced technique can find hidden infections and guide better treatment.…

This study tests whether a DNA-based test (PCR) can diagnose urinary tract infections (UTIs) faster and more accurately than the usual urine culture. About 136 adults with UTI symptoms will be randomly assigned to one of the two testing methods. Researchers will track how quickly…

This study looks at whether a single injection of the antibiotic amikacin can effectively treat uncomplicated bladder infections in women visiting the emergency department. Instead of taking pills for several days, participants get one shot into a muscle or vein. The goal is to s…

This study looks at whether a 21-day spa program, including mineral water baths and exercise, can help people with chronic kidney and urinary tract problems. Researchers will check 150 adults (ages 40-70) before and after treatment using blood tests, urine tests, and quality-of-l…

This study looks at whether scheduling automatic follow-up appointments after a child leaves the hospital is better than letting parents decide if one is needed. About 2,674 children hospitalized for infections like pneumonia or urinary tract infections will take part. The goal i…

This early-stage study is testing a new drug called JKN2501 in 66 healthy adults in China to see if it is safe and how the body processes it. Participants will receive either the drug or a placebo by IV, and researchers will monitor for side effects and measure drug levels in blo…

This study tests a prediction model to help doctors decide when antibiotics are truly needed for urinary tract infections (UTIs) in the emergency room. About 47 women with UTIs will be enrolled. The goal is to reduce unnecessary antibiotic use and fight antibiotic resistance.