New antibiotic JKN2501 enters first human tests

NCT ID NCT07207291

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-phase trial tests the safety and tolerability of a new antibiotic called JKN2501 in 66 healthy adults in China. Participants receive either the drug or a placebo by IV infusion, and researchers monitor for side effects and how the drug moves through the body. The goal is to see if it is safe enough to study further for treating bacterial infections like urinary tract, abdominal, and respiratory infections.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
JKN2501 (an experimental antibiotic given by IV infusion)
What this could lead to
If safe, this could lead to a new antibiotic for bacterial infections that are hard to treat.
What could go wrong
This is a very early Phase 1 trial in only 66 healthy people, so it is not yet tested in patients. The drug may cause side effects or fail in later studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The Third hospital of Changsha

    RECRUITING

    Changsha, Hunan, 410035, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.