Could a simple pill replace the IV drip for ER infections?

NCT ID NCT06715306

Recruiting now Disease control Sponsor: University of Southern Denmark Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving oral antibiotics instead of IV antibiotics is just as safe and effective for patients with common infections like pneumonia, urinary tract infections, and cellulitis. About 4,000 adults in Danish emergency rooms will be randomly assigned to start oral antibiotics right away or continue with IV treatment. The goal is to see if oral treatment can keep patients healthy and out of the hospital just as well as IV, potentially allowing many to go home sooner.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral antibiotics
What this could lead to: If oral antibiotics work as well as IV, many patients could be treated at home or discharged sooner, saving hospital resources and reducing time away from home.
What could go wrong: This is a large trial but still testing whether oral antibiotics are safe and effective enough for patients who would normally get IV. Some patients may need IV if oral fails or causes side effects.

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Conditions

The condition(s) this trial relates to.

cellulitis respiratory tract infectious disorder urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CELLULITIS RESPIRATORY TRACT INFECTIONS URINARY TRACT INFECTIONS

Contacts and locations

Locations

Amager and Hvidovre Hospital
ACTIVE_NOT_RECRUITING

Hvidovre, 2650, Denmark
Bispebjerg and Frederiksberg Hospital
ACTIVE_NOT_RECRUITING

Copenhagen, 2400, Denmark
Esbjerg and Grindsted Sygehus
RECRUITING

Esbjerg, 6700, Denmark
Herlev and Gentofte Hospital
ACTIVE_NOT_RECRUITING

Herlev, 2730, Denmark
Nordsjællands Hospital
RECRUITING

Copenhagen, Denmark
Sygehus Lillebælt
RECRUITING

Kolding, 6000, Denmark
Sygehus Sønderjylland
RECRUITING

Aabenraa, Southern Denmark, 6200, Denmark

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