Could a common painkiller speed up cellulitis recovery?

NCT ID NCT07665476

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

Cellulitis is a painful bacterial skin infection. This study tests whether adding naproxen (an anti-inflammatory drug) to standard antibiotics helps reduce redness and pain faster than antibiotics alone. About 884 adults with cellulitis will take either naproxen or a placebo for 7 days, and doctors will check if the infection area shrinks by at least 20% after 72 hours.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

naproxen

What this could lead to

If it works, adding naproxen to antibiotics could speed up recovery, reduce pain, and lower treatment failure for cellulitis patients.

What could go wrong

This is a large trial, but earlier studies were too small to confirm benefit. Naproxen may not help, and like all NSAIDs, it carries risks like stomach irritation or kidney issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cellulitis Infections infectious disease skin disorder caused by infection skin infection Soft Tissue Infections

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Ottawa Hospital

    Ottawa, Ontario, K1y 4E9, Canada

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••