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Rapid molecular tests could help doctors prescribe antibiotics more precisely

NCT ID NCT07684300

Recruiting now Disease control Sponsor: Maria Espinosa Perez Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This trial investigates whether combining rapid molecular microbiology tests with predefined clinical criteria helps doctors optimize antibiotic use in hospitalized adults receiving strong, broad-spectrum antibiotics. The study compares a protocolized antimicrobial stewardship strategy against standard practice. Researchers will measure how long patients are on high-impact antibiotics, treatment appropriateness, and safety outcomes like side effects, readmission, and mortality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Protocolized Antimicrobial Stewardship Strategy (behavioral intervention integrating multiplex PCR results with clinical criteria)
What this could lead to
If successful, this approach could help hospitals reduce unnecessary antibiotic use, lower the risk of antibiotic resistance, and improve patient outcomes without harming safety.
What could go wrong
The trial is relatively small (250 participants) and tests a behavioral strategy rather than a drug, so results may not apply to all hospitals or patient groups. The strategy may not reduce antibiotic use as expected or could lead to unintended treatment changes.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANTIMICROBIAL RESISTANCE ANTIMICROBIAL STEWARDSHIP PROGRAM INFECTION MULTIPLEX PCR

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Hospital General Universitario de Elche

    RECRUITING

    Elche, Alicante, 03203, Spain

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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