Faster UTI diagnosis? DNA test takes on Old-School culture

NCT ID NCT06808451

Recruiting now Diagnosis Sponsor: University Hospitals Cleveland Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new DNA-based test (PCR) to the standard urine culture for diagnosing urinary tract infections (UTIs) in adults. About 136 people with UTI symptoms will be randomly assigned to one of the two tests. Researchers will track how quickly treatment starts, how symptoms change, and whether antibiotics need to be adjusted. The goal is to see if the faster DNA test leads to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: DNA PCR test
What this could lead to: If successful, this could show that DNA PCR testing leads to faster, more accurate UTI diagnosis and treatment.
What could go wrong: This is a small, early-stage trial (136 people) comparing two diagnostic methods, not a treatment itself. The DNA PCR test may not improve symptoms or antibiotic use enough to replace standard culture.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

URINARY TRACT INFECTIONS

Contacts and locations

Locations

University Hospitals
RECRUITING

Cleveland, Ohio, 44106, United States

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