New DNA test catches UTIs that standard cultures miss

NCT ID NCT05206500

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether next-generation sequencing (NGS), a DNA-based method, can detect bacteria in urine when standard lab cultures show very low or no growth. About 100 women with UTI symptoms but inconclusive standard tests will provide urine samples for NGS analysis. The goal is to see if NGS can identify hidden infections and guide more effective antibiotic treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Next Generation Sequencing (NGS) device

What this could lead to

If successful, this could lead to more accurate diagnosis of urinary tract infections in patients whose standard tests are inconclusive.

What could go wrong

This is a small, early-phase study (100 participants) and NGS may not always translate into better treatment outcomes. The approach is still experimental.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wake Forest Health Sciences

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••