URINARY TRACT INFECTIONS
Clinical trials for URINARY TRACT INFECTIONS explained in plain language.
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Gut bacteria transplant shows promise for recurring UTIs
Disease control CompletedThis study tested whether transplanting healthy gut bacteria (washed microbiota transplantation) could help people who get frequent urinary tract infections (UTIs). Thirty adults with recurrent UTIs received the treatment through a tube into the gut. Researchers tracked how many …
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE1, PHASE2 • Sponsor: The Second Hospital of Nanjing Medical University • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Gum treatment may lower prostate inflammation and UTI risk
Disease control CompletedThis study looked at whether deep cleaning of the gums (non-surgical periodontal therapy) could reduce prostate-specific antigen (PSA) levels and urinary tract infections in men with both gum disease and chronic prostatitis or recurrent UTIs. Sixty men were split into three group…
Matched conditions: URINARY TRACT INFECTIONS
Phase: NA • Sponsor: University of Salamanca • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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New antibiotic GSK3882347 tested for UTIs in early trial
Disease control CompletedThis early-stage trial tested an experimental antibiotic called GSK3882347 in 140 women with uncomplicated urinary tract infections (UTIs). Participants received either the new drug, a standard antibiotic (nitrofurantoin), or a placebo for 5 days. The study measured how well the …
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE1 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Could a vaginal gel cut recurrent UTIs in menopause?
Disease control CompletedThis study tested whether an over-the-counter vaginal moisturizing gel, called BioNourish, could reduce recurrent urinary tract infections (UTIs) in menopausal women. The idea is that the gel helps restore a healthy vaginal microbiome, which may protect against UTIs. Eight post-m…
Matched conditions: URINARY TRACT INFECTIONS
Phase: NA • Sponsor: Vaginal Biome Science • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New antibiotic match for tough UTIs?
Disease control CompletedThis study tested if the antibiotic temocillin works as well as a stronger antibiotic (carbapenem) for treating urinary tract infections caused by resistant bacteria. 29 hospitalized adults took part. The goal was to see if both treatments could clear the infection and symptoms. …
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Which UTI antibiotic works best? new study compares four options
Disease control CompletedThis study tested four different short antibiotic courses in 1,000 women with uncomplicated lower urinary tract infections. Participants received either a two-day course of fosfomycin, a three-day course of pivmecillinam, a five-day course of nitrofurantoin, or a single dose of f…
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE4 • Sponsor: Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina • Aim: Disease control
Last updated Jun 26, 2026 14:59 UTC
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Cow colostrum may shield kids from recurrent UTIs
Prevention CompletedThis study tested whether a supplement made from bovine colostrum (the first milk from cows) can prevent repeated urinary tract infections (UTIs) in children. Sixty children with a history of recurrent UTIs took part. The goal was to see if this natural prebiotic could reduce the…
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE2 • Sponsor: Ain Shams University • Aim: Prevention
Last updated Jun 27, 2026 08:08 UTC
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New antibiotic shows promise for fast UTI symptom relief in women
Symptom relief CompletedThis completed Phase 3 trial tested the antibiotic gepotidacin in 97 adolescent and adult women with uncomplicated urinary tract infections (UTIs). The goal was to see if symptoms like pain and urgency improved within 24 hours. Researchers measured symptom scores and safety. The …
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Vaginal laser shows promise for menopause symptoms and incontinence
Symptom relief CompletedThis study tested a fractional carbon dioxide laser treatment for women with vaginal and urinary symptoms like dryness, burning, pain during sex, and incontinence. One hundred women received three laser sessions about six weeks apart. The main goal was to see if symptoms improved…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: Corewell Health East • Aim: Symptom relief
Last updated Jun 27, 2026 08:06 UTC
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Antibiotics before kidney drainage: help or hype?
Knowledge-focused CompletedThis study looked at whether giving antibiotics before a kidney drainage procedure (called percutaneous nephrostomy) prevents urinary tract infections in cancer patients whose urinary tract is blocked by a tumor. Researchers reviewed records of 320 cancer patients who had the pro…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: Barretos Cancer Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Video team cuts unnecessary antibiotic use in rural hospitals
Knowledge-focused CompletedThis study tested a program where rural hospitals connect with an infectious disease expert through video calls to improve antibiotic use. The goal was to reduce unnecessary antibiotics and fight drug-resistant infections. Eight VA medical centers participated, and the approach h…
Matched conditions: URINARY TRACT INFECTIONS
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:28 UTC
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Scientists investigate why vaginal estrogen only works for half of women with recurrent UTIs
Knowledge-focused CompletedThis study looked at 27 postmenopausal women with frequent urinary tract infections (UTIs) to understand why vaginal estrogen therapy prevents UTIs in only about half of them. Researchers examined changes in bacteria in the vagina and bladder, as well as immune responses, before …
Matched conditions: URINARY TRACT INFECTIONS
Phase: PHASE4 • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Rethinking Pre-Surgery urine tests: could skipping a second culture be safe?
Knowledge-focused CompletedThis study looked at 147 kidney stone patients who had a positive urine culture before a minimally invasive surgery called mini-PCNL. Doctors gave them antibiotics and then checked if a follow-up urine culture was needed to predict infections after surgery. The goal was to see if…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: Junhao Zheng • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Urine test changes may flag infection risk after kidney stone surgery
Knowledge-focused CompletedThis study examined 346 adults who had kidney stone surgery to see if changes in their urine white blood cells and nitrite levels before the operation could predict serious infections like fever or sepsis afterward. The goal was to find a faster, simpler way to identify high-risk…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Should you remove kidney stones to stop UTIs? study seeks answers
Knowledge-focused CompletedThis study followed 94 adults who have both recurrent urinary tract infections and kidney stones that are not blocking the kidney. Researchers wanted to see if surgically removing these stones reduces the number of future UTIs compared to just monitoring them. Patients chose with…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: Vanderbilt University Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:55 UTC
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Vegetarian diet linked to lower risk of dementia, heart disease, and more in massive study
Knowledge-focused CompletedThis completed study followed over 18,000 Taiwanese Buddhists to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers compared health records…
Matched conditions: URINARY TRACT INFECTIONS
Sponsor: Dalin Tzu Chi General Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:57 UTC