Could a vaginal gel cut recurrent UTIs in menopause?

NCT ID NCT05573334

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether an over-the-counter vaginal moisturizing gel, called BioNourish, could reduce recurrent urinary tract infections (UTIs) in menopausal women. The idea is that the gel helps restore a healthy vaginal microbiome, which may protect against UTIs. Eight post-menopausal women with a history of repeat UTIs used the product for six months, and researchers tracked changes in vaginal bacteria, pH, and UTI frequency. Because it's a very small pilot, the results are preliminary and need larger studies to confirm.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
BioNourish vaginal moisturizing gel (device)
What this could lead to
If it works, this could offer a non-hormonal, over-the-counter option to help menopausal women reduce recurrent urinary tract infections.
What could go wrong
This is a very small pilot study with only 8 participants, so results may not apply widely. The device is already on the market, but its effect on UTI frequency is still uncertain.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Center for Urogynecology & Pelvic Reconstructive Surgery

    Newark, Delaware, 19713, United States

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