Could fewer antibiotics be better for older women with urinary symptoms?

NCT ID NCT07686055

First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time

Summary

This trial tests three ways to manage urinary symptoms in women aged 65 and older who have frequent urinary tract infections. Some participants receive antibiotics right away, while others get treatment only after a urine test or a lab culture. The goal is to find out which approach works best—relieving symptoms while avoiding unnecessary antibiotics. The study aims to improve care and reduce antibiotic overuse in this group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Antibiotics (nitrofurantoin, trimethoprim/sulfamethoxazole, fosfomycin, ciprofloxacin, or cephalexin)
What this could lead to
If successful, this could help doctors know which older women truly need antibiotics for urinary symptoms and which can safely avoid them, reducing overtreatment and antibiotic resistance.
What could go wrong
This is a small trial (90 participants) and results may not apply to all older women. The different antibiotic strategies may not show clear differences in outcomes.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC-Magee Womens Hospital

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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