Heparin bladder rinse may cut recurrent UTIs in women

NCT ID NCT02246270

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase trial tested whether putting heparin directly into the bladder can reduce the number of urinary tract infections (UTIs) in women who get them often. 34 women with recurrent UTIs received either heparin or a placebo (saline) bladder wash. The study measured how many UTIs they had over 6 months and how long it took for another infection to occur.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Heparin (bladder instillation)
What this could lead to
If it works, this could offer a new option to prevent recurrent urinary tract infections in women.
What could go wrong
This is a very early, small trial with only 34 participants. The results may not apply to everyone, and heparin's effectiveness is not yet proven.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Oklahoma-Tulsa OB/GYN Dept and OU-Physicians

    Tulsa, Oklahoma, 74135, United States

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