Can a weekly pill and weight lifting rebuild aging bones?

NCT ID NCT07191353

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a weekly dose of everolimus (a drug similar to rapamycin), resistance training three times a week, or both together can improve bone formation in women aged 60-75 with low bone mass. Researchers will measure bone markers, density, and muscle function over 24 weeks. The goal is to find a safe way to prevent osteoporosis without long-term medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Everolimus (a rapamycin analog) and resistance training

What this could lead to

If successful, this could point toward a drug-exercise combination to strengthen bones and reduce fracture risk in older women.

What could go wrong

This is a small, early-phase trial with 148 participants. The drug may cause side effects, and results may not apply to all women. The combination might not work better than exercise alone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Bone Diseases, Metabolic osteoporosis prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Endocrinology, Odense University Hospital

    RECRUITING

    Odense, Region Syddanmark, 5000, Denmark

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institute of Sports Medicine, Bispebjerg Hospital

    RECRUITING

    Bispebjerg, Region Sjælland, 2200, Denmark

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact