OSTEOPENIA

This study tests whether veverimer, a drug that lowers acid levels in the body, can reduce bone breakdown in adults aged 50 and older with osteopenia (low bone density). Sixty participants will take either veverimer or a placebo daily or every other day for 8 weeks. Researchers w…

This study looks at whether a weekly dose of everolimus (a rapamycin-like drug), resistance training, or both can help build bone and muscle in women aged 60-75 who have lower bone density but not full osteoporosis. About 148 women will be randomly assigned to take the drug, a pl…

This study tests whether whole-body vibration therapy can help bone health and physical function in women with low bone density (osteopenia) after total knee replacement. 48 women will be split into three groups: vibration alone, vibration with exercise, or standard rehab. The go…

This study looks at whether a single dose of zoledronic acid can prevent bone loss that often happens when people start HIV medications. About 110 adults newly diagnosed with HIV will either receive the drug or just be monitored. Researchers will track bone density over four year…

This study is testing a portable ultrasound device that uses sound waves to measure bone density in the lower leg, without any radiation. Researchers will compare its results to standard DXA X-ray scans in 350 healthy men and women aged 21 to 55. The goal is to see if the new dev…

This study aims to validate and check the reproducibility of laboratory tests, equipment, and techniques used in research on chronic diseases like obesity, diabetes, and heart disease. Researchers will compare old and new testing methods to ensure results are accurate and consist…

This study tests a new, safe ultrasound technology called REMS to measure bone density in children aged 5 to 18 who have conditions that weaken bones, like brittle bone disease or osteoporosis. Unlike standard X-ray methods, REMS uses no radiation. The goal is to see how well REM…