Odense University Hospital

This Phase 2 trial tests whether a combination of three drugs—dasatinib, quercetin, and nicotinamide riboside—can improve bone health in 120 adults aged 60-90 with osteopenia or osteoporosis. The goal is to see if these 'senolytic' drugs can clear aging cells from the skeleton an…

This phase 2 trial is testing whether oral semaglutide (Rybelsus), a drug already used for type 2 diabetes, can improve bone health in people aged 50-85 with diabetes and weak bones (osteopenia). Over 52 weeks, 64 participants will receive either the drug or a placebo. Researcher…

This study tests whether flushing catheters with special solutions (Uro-Tainer with citric acid or polihexanide) can reduce blockages and infections compared to standard saline. About 70 adults with permanent catheters who have had blockages before will take part. The goal is to …

This study tests whether robot-assisted leg exercises can prevent older patients from losing strength and independence during a hospital stay. 488 patients aged 65 and older will either receive robot-guided training or standard care. The goal is to see if the robot helps them wal…

This study tests whether a weekly dose of everolimus (a drug that targets aging pathways) and/or a fun exercise program called 'Football Fitness' can prevent the rapid bone loss that happens after menopause. 136 healthy women aged 45-60 will be assigned to one of four groups: exe…

This study tests whether a digital version of cognitive behavioral therapy for insomnia (CBT-I) can improve sleep and reduce pain in 140 adults with chronic pain and insomnia. Participants will either receive the digital CBT-I program or digital sleep hygiene education. The goal …

This study follows 225 pregnant women—some who had gastric bypass or sleeve gastrectomy, and some without surgery—to see how blood sugar changes affect fetal growth. Participants wear a continuous glucose monitor and activity tracker for 10 days each trimester. The goal is to lea…

This study looks at whether using an activity tracker with motivational feedback helps people become more active after knee replacement surgery compared to using a tracker without feedback. About 152 adults aged 40-85 scheduled for knee replacement will take part. The goal is to …

This study compares 20 women who had gestational diabetes with 20 who did not, all matched by age and weight. Researchers will measure body composition, insulin sensitivity, and other metabolic markers before and after 8 weeks of high-intensity interval training. The goal is to u…

This study looks for a biomarker to identify people at risk of bone loss from glucocorticoid medications like prednisolone. 36 healthy volunteers will take either prednisolone or a placebo for seven days. Researchers will measure bone turnover markers in blood and collect bone, m…