Blood test may predict Steroid-Induced bone loss
NCT ID NCT06421597
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks for a biomarker to identify people at risk of bone loss from glucocorticoid medications like prednisolone. 36 healthy volunteers will take either prednisolone or a placebo for seven days. Researchers will measure bone turnover markers in blood and collect bone, marrow, and fat samples to find a way to predict individual risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prednisolone
What this could lead to
If successful, this could lead to a blood test that identifies who is at risk of bone loss from steroid medications, allowing for personalized monitoring or prevention.
What could go wrong
This is a small, early-phase study in healthy volunteers, not patients. The biomarker may not work in real-world settings or predict long-term bone loss.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital of South West Jutland
Esbjerg, 6700, Denmark
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Odense University Hospital
Odense C, 5000, Denmark